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GSK-2830371

GSK-2830371

Product ID G7240
Cas No. 1404456-53-6
Purity ≥98%
Product Unit SizeCostQuantityStock
1 mg $67.80 In stock
5 mg $117.20 In stock
10 mg $217.90 In stock
25mg $309.80 Please Inquire
25 mg $443.30 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

GSK-2830371 is an inhibitor of wild-type p53-induced phosphatase 1 (Wip1) that exhibits anticancer chemotherapeutic activity. In animal models of lymphoma, GSK-2830371 inhibits cell growth and tumor growth. In neuroblastoma cells, this compound induces cell death.

Product Info

Cas No.

1404456-53-6

Purity

≥98%

Formula

C23H29ClN4O2S

Formula Wt.

461.02

IUPAC Name

5-{[(5-Chloro-2-methyl-3-pyridinyl)amino]methyl}-N-[(2S)-3-cyclopentyl-1-(cyclopropylamino)-1-oxo-2-propanyl]-2-thiophenecarboxamide

Solubility

DMSO 92 mg/mL (199.55 mM) Ethanol 92 mg/mL warmed (199.55 mM) Water Insoluble

Appearance

Yellow to off white powder

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

G7240 MSDS PDF

Info Sheet

G7240 Info Sheet PDF

References

Richter M, Dayaram T, Gilmartin AG, et al. WIP1 Phosphatase as a Potential Therapeutic Target in Neuroblastoma. PLoS One. 2015 Feb 6;10(2):e0115635. PMID: 25658463.

Gilmartin AG, Faitg TH, Richter M, et al. Allosteric Wip1 phosphatase inhibition through flap-subdomain interaction. Nat Chem Biol. 2014 Mar;10(3):181-7. PMID: 24390428.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
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