Description
H-151 is a STING antagonist.
H-151
Product ID H000051
Cas No. 941987-60-6
Purity ≥99%
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Product Info
| Cas No. | 941987-60-6 |
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| Purity | ≥99% |
| Formula | C17H17N3O |
| Formula Wt. | 279.34 |
| Chemical Name | 1-(4-Ethylphenyl)-3-(1H-indol-3-yl) urea |
| IUPAC Name | 1-(4-ethylphenyl)-3-(1H-indol-3-yl)urea |
| Synonym | H151; N-(4-ethylphenyl)-N'-1H-indol-3-yl-urea |
| Appearance | Pale yellow to white solid |
Shipping and Storage
| Store Temp | -20°C |
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| Ship Temp | Ambient |
Downloads
| Info Sheet |
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References
Zeng H, Gao Y, Yu W, et al. Pharmacological inhibition of STING/TBK1 signaling attenuates myeloid fibroblast activation and macrophage to myofibroblast transition in renal fibrosis. Front Pharmacol. 2022 Jul 18;13:940716. PMID: 35924048
Sun C, Wu G, Zhang Z, et al. Protein tyrosine phosphatase receptor type D regulates neuropathic pain after nerve injury via the STING-IFN-I pathway. Front Mol Neurosci. 2022 Apr 14;15:859166. PMID: 35493326
Hu S, Gao Y, Gao R, et al. The selective STING inhibitor H-151 preserves myocardial function and ameliorates cardiac fibrosis in murine myocardial infarction. Int Immunopharmacol. 2022 Jun;107:108658. PMID: 35278833