• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Hexamethylene Bisacetamide

Hexamethylene Bisacetamide

Product ID H1892
Cas No. 3073-59-4
Purity ≥99%
Product Unit SizeCostQuantityStock
25 g $80.30 In stock
50 g $128.20 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Hexamethylene bisacetamide (HMBA) activates hexamethylene bisacetamide-inducible protein 1 (HEXIM1), inhibiting transcription elongation factor b (P-TEFb), a regulator of RNA polymerase II and mRNA synthesis. HMBA exhibits anticancer activity and is used to induce cellular differentiation and apoptosis in cancer cells. HMBA also inhibits activation of NF-κB, Akt, and ERK.

Product Info

Cas No.

3073-59-4

Purity

≥99%

Formula

C10H20N2O2

Formula Wt.

200.28

Chemical Name

N,N'-Hexamethylene (bis)acetamide

IUPAC Name

N-(6-acetamidohexyl)acetamide

Synonym

N,N'-Diacetyl-1,6-hexanediamine, HMBA

Melting Point

128-129°C

Solubility

Soluble in water or ethanol.

Appearance

White crystalline powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

H1892 MSDS PDF

Info Sheet

H1892 Info Sheet PDF

References

Lew QJ, Chia YL, Chu KL, et al. Identification of HEXIM1 as a positive regulator of p53. J Biol Chem. 2012 Oct 19;287(43):36443-54. PMID: 22948151.

Dey A, Wong E, Kua N, et al. Hexamethylene bisacetamide (HMBA) simultaneously targets AKT and MAPK pathway and represses NF kappaB activity: implications for cancer therapy. Cell Cycle. 2008 Dec;7(23):3759-67. PMID: 19029824.

Zhang Z, Liong EC, Lau TY, et al. Induction of apoptosis by hexamethylene bisacetamide is p53-dependent associated with telomerase activity but not with terminal differentiation. Int J Oncol. 2000 May;16(5):887-92. PMID: 10762623.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • S1059

    Scopolamine Hydrobromide Trihydrate

    Tropane alkaloid found in Solanaceae plants; M1...

    ≥98%
  • H9613

    N-(4-Hydroxyphenyl)retinamide

    Retinol (vitamin A) analog, binds RBP4; Des1 in...

    ≥98%
  • W5726

    Wogonin

    Flavonoid found in Scutellaria; CDK9 inhibitor....

    ≥98%
  • V344761

    Vitamin K2

    2-methyl-1,4-naphthoquinone derivative

    ≥98%
  • N3310

    Nicotinamide

    Amide form of vitamin B3 required for productio...

    ≥98%
  • S6134

    Spinorphin, bovine

    Endogenous heptapeptide; P2X3 and N-formylpepti...

    ≥95%
  • A6800

    AR-A014418

    GSK-3β inhibitor.

    ≥98%
  • K7600

    KT5720

    PKA and PDK1 inhibitor, HCN channel blocker, po...

    ≥98%
  • P698579

    Propantheline Bromide

    Antimuscarinic

    ≥98%
  • A5059

    Amoxapine

    5-HT2/3/6/7, D2/3/4, histamine H1, α1-adrenerg...

    ≥98%
  • C0252

    Canertinib Dihydrochloride

    EGFR inhibitor.

    ≥98%
  • R2812

    Recombinant HIV-1 gp-120

    Recombinant HIV glycoprotein antigen fragment.<...

    ≥95%
  • G4796

    Glycerol Monolaurate

    Surfactant found in coconut oil.

    ≥98%
  • P0245

    Palmatine Chloride Hydrate

    Isoquinoline alkaloid found in Corydalis, Phell...

    ≥96%
  • E6231

    (−)-Epicatechin

    Flavanol originally found in Camilla (green tea...

    ≥93%
  • R5661

    Ropinirole Hydrochloride

    Indoline; D2/3 agonist.

    ≥99%
  • Q8139

    Quizartinib

    FLT3, c-Kit, PDGFR inhibitor.

    ≥98%
  • G691343

    Griseofulvin

    Fungistatic

    ≥98%
  • B1652

    Benzo[a]pyrene

    Polycyclic aromatic hydrocarbon (PAH) found in ...

    ≥98%
  • P014442

    Palbociclib

    CDK4/6 inhibitor.

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only