Description
JAK2 inhibitor V (Z3) is an inhibitor of JAK2 that exhibits anticancer activity. In erythroleukemia cells, this compound induces cell cycle arrest and suppresses cellular proliferation.
| Product Unit Size | Cost | Quantity | Stock |
|---|
JAK2 inhibitor V (Z3) is an inhibitor of JAK2 that exhibits anticancer activity. In erythroleukemia cells, this compound induces cell cycle arrest and suppresses cellular proliferation.
| Cas No. | 195371-52-9 |
|---|---|
| Purity | ≥98% |
| Formula | C23H24N2O |
| Formula Wt. | 344.46 |
| IUPAC Name | 2-Methyl-1-phenyl-4-(2-pyridinyl)-2-[2-(2-pyridinyl)ethyl]-1-butanone |
| Synonym | JAK2 inhibitor V, Z3 |
| Solubility | Soluble in DMSO or Ethanol |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet | |
| Brochures |
Sayyah J, Magis A, Ostrov DA, et al. Z3, a novel Jak2 tyrosine kinase small-molecule inhibitor that suppresses Jak2-mediated pathologic cell growth. Mol Cancer Ther. 2008 Aug;7(8):2308-18. PMID: 18723478.
Glucocorticoid
SERT inhibitor.
Synthesis impurity
Aminothiol, CoA component; ulcer inducer.
Non-competitive inhibitor of xanthine oxidase.<...
MEK1/2 inhibitor.
Natriuretic, vasodilatory peptide; B1/2 agonist...
Tetracyclic sesterpenoid phytotoxin.
Isoquinoline alkaloid found in various plant so...
Degrades of BET proteins.
Inhibitor of EGFR/HER2 (ErbB2).
ALK inhibitor.
Phenylamino pyridine; Abl, c-Kit, PDGFR, PP2A i...
Synthesis intermediate
Protease inhibitor.
Antimicrobial peptide found in Hyalophora cecro...
Cannabinoid receptor 2 selective agonist.
p110δ PI3K inhibitor.
Macrolide antibiotic; vacuolar H+ ATPase inhibi...
Endogenous adhesion molecule, binds PKC, calmod...