Description
JAK2 inhibitor V (Z3) is an inhibitor of JAK2 that exhibits anticancer activity. In erythroleukemia cells, this compound induces cell cycle arrest and suppresses cellular proliferation.
| Product Unit Size | Cost | Quantity | Stock |
|---|
JAK2 inhibitor V (Z3) is an inhibitor of JAK2 that exhibits anticancer activity. In erythroleukemia cells, this compound induces cell cycle arrest and suppresses cellular proliferation.
| Cas No. | 195371-52-9 |
|---|---|
| Purity | ≥98% |
| Formula | C23H24N2O |
| Formula Wt. | 344.46 |
| IUPAC Name | 2-Methyl-1-phenyl-4-(2-pyridinyl)-2-[2-(2-pyridinyl)ethyl]-1-butanone |
| Synonym | JAK2 inhibitor V, Z3 |
| Solubility | Soluble in DMSO or Ethanol |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet | |
| Brochures |
Sayyah J, Magis A, Ostrov DA, et al. Z3, a novel Jak2 tyrosine kinase small-molecule inhibitor that suppresses Jak2-mediated pathologic cell growth. Mol Cancer Ther. 2008 Aug;7(8):2308-18. PMID: 18723478.
Synthetic type II pyrethroid insecticide; prote...
Peptide; peptidoglycan inhibitor.
Salicylic acid prodrug, NSAID; weak COX-1/2 inh...
Pentacyclic triterpene found in various plant s...
Endogenous amino acid, precursor of 5-HT and me...
HDAC inhibitor, RNA splicing modulator.
Byproduct of L-arginine metabolism found in wat...
S-adenosylmethionine nucleoside analog; methylt...
M4 mAChR agonist, 5-HT1A partial agonist, M1/2/...
β2-adrenergic agonist.
SIRT1 inhibitor.
Saponin found in Bupleurum, Heteromorpha, and S...
Decreases expression of MMPs, PGE2, and COX-2, ...
EZH2 HMT inhibitor.
p53 activator.
Diterpene found in Anisomeles.
Triterpene found in species of Citrus; HIV-1 pr...
Amino amide; voltage-gated Na+, BK/SK, Kv1, Kv3...
Folate source co-administered with methotrexate...
Nucleoside (deoxycytidine) analog; DNMT inhibit...