Description
JAK2 inhibitor V (Z3) is an inhibitor of JAK2 that exhibits anticancer activity. In erythroleukemia cells, this compound induces cell cycle arrest and suppresses cellular proliferation.
| Product Unit Size | Cost | Quantity | Stock |
|---|
JAK2 inhibitor V (Z3) is an inhibitor of JAK2 that exhibits anticancer activity. In erythroleukemia cells, this compound induces cell cycle arrest and suppresses cellular proliferation.
| Cas No. | 195371-52-9 |
|---|---|
| Purity | ≥98% |
| Formula | C23H24N2O |
| Formula Wt. | 344.46 |
| IUPAC Name | 2-Methyl-1-phenyl-4-(2-pyridinyl)-2-[2-(2-pyridinyl)ethyl]-1-butanone |
| Synonym | JAK2 inhibitor V, Z3 |
| Solubility | Soluble in DMSO or Ethanol |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet | |
| Brochures |
Sayyah J, Magis A, Ostrov DA, et al. Z3, a novel Jak2 tyrosine kinase small-molecule inhibitor that suppresses Jak2-mediated pathologic cell growth. Mol Cancer Ther. 2008 Aug;7(8):2308-18. PMID: 18723478.
α2-adrenergic and imidazoline-1 antagonist, AT...
Diterpene found in brewed, unfiltered coffee; F...
Fungal metabolite produced by Penicillium speci...
Side chain attached to various taxanes.
Pyrimidine derivative; kinesin Eg5 inhibitor.
Endogenous neuropeptide hormone, involved in so...
Endogenous peptide, involved in vasoconstrictio...
Histone H2-derived antimicrobial peptide found ...
Nrf2-Keap1-ARE complex activator.
BHA derivative; potential Ca2+ ATPase inhibitor...
Diterpene compound originally found in Rosmarin...
Potent and selective inhibitor
Kv7 K+ channel activator, NMDA antagonist, GABA...
Polypeptide; serine protease inhibitor.
Acyl-CoA synthetase inhibitor.
Src and Abl inhibitor.
Survivin inhibitor.
β1/2-adrenergic antagonist.
Optically active cysteine derivative found in A...