Description
JAK2 inhibitor V (Z3) is an inhibitor of JAK2 that exhibits anticancer activity. In erythroleukemia cells, this compound induces cell cycle arrest and suppresses cellular proliferation.
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JAK2 inhibitor V (Z3) is an inhibitor of JAK2 that exhibits anticancer activity. In erythroleukemia cells, this compound induces cell cycle arrest and suppresses cellular proliferation.
| Cas No. | 195371-52-9  | 
			
|---|---|
| Purity | ≥98%  | 
			
| Formula | C23H24N2O  | 
			
| Formula Wt. | 344.46  | 
			
| IUPAC Name | 2-Methyl-1-phenyl-4-(2-pyridinyl)-2-[2-(2-pyridinyl)ethyl]-1-butanone  | 
			
| Synonym | JAK2 inhibitor V, Z3  | 
			
| Solubility | Soluble in DMSO or Ethanol  | 
			
| Store Temp | -20°C  | 
			
|---|---|
| Ship Temp | Ambient  | 
			
| MSDS | |
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| Info Sheet | |
| Brochures | 
Sayyah J, Magis A, Ostrov DA, et al. Z3, a novel Jak2 tyrosine kinase small-molecule inhibitor that suppresses Jak2-mediated pathologic cell growth. Mol Cancer Ther. 2008 Aug;7(8):2308-18. PMID: 18723478.
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