Description
JAK2 inhibitor V (Z3) is an inhibitor of JAK2 that exhibits anticancer activity. In erythroleukemia cells, this compound induces cell cycle arrest and suppresses cellular proliferation.
Product Unit Size | Cost | Quantity | Stock |
---|
JAK2 inhibitor V (Z3) is an inhibitor of JAK2 that exhibits anticancer activity. In erythroleukemia cells, this compound induces cell cycle arrest and suppresses cellular proliferation.
Cas No. | 195371-52-9 |
---|---|
Purity | ≥98% |
Formula | C23H24N2O |
Formula Wt. | 344.46 |
IUPAC Name | 2-Methyl-1-phenyl-4-(2-pyridinyl)-2-[2-(2-pyridinyl)ethyl]-1-butanone |
Synonym | JAK2 inhibitor V, Z3 |
Solubility | Soluble in DMSO or Ethanol |
Store Temp | -20°C |
---|---|
Ship Temp | Ambient |
MSDS | |
---|---|
Info Sheet | |
Brochures |
Sayyah J, Magis A, Ostrov DA, et al. Z3, a novel Jak2 tyrosine kinase small-molecule inhibitor that suppresses Jak2-mediated pathologic cell growth. Mol Cancer Ther. 2008 Aug;7(8):2308-18. PMID: 18723478.
Macrocyclic lactone avermectin; GABA antagonist...
Benzimidazole; microtubule polymerization inhib...
Sulforaphane-cysteine conjugate.
Smoothened agonist.
Microtubule polymerization inhibitor, potential...
Antimicrobial peptide found in amphibians.
Semi-synthetic vinca alkaloid from Catharanthus...
Alkaloid compound originally found in Corydalis...
β2-adrenergic agonist, BChE inhibitor.
PI3K inhibitor.
A fungal metabolite that inhibits protein synth...
Alkyl sulfonate; DNA alkylator.
Peptide hormone, neurotensin analog found in am...
TTK/CLK2 inhibitor.
Triazole; 14-α demethylase and aromatase inhib...
α2-adrenergic agonist.
Peptide, involved in synapse formation and cell...
mTOR inhibitor.
Found in Capsicum; TRPV agonist.
Purine, purvalenol A analog; CDK2, Cdc28p, Pho8...