Description
JAK2 inhibitor V (Z3) is an inhibitor of JAK2 that exhibits anticancer activity. In erythroleukemia cells, this compound induces cell cycle arrest and suppresses cellular proliferation.
Product Unit Size | Cost | Quantity | Stock |
---|
JAK2 inhibitor V (Z3) is an inhibitor of JAK2 that exhibits anticancer activity. In erythroleukemia cells, this compound induces cell cycle arrest and suppresses cellular proliferation.
Cas No. | 195371-52-9 |
---|---|
Purity | ≥98% |
Formula | C23H24N2O |
Formula Wt. | 344.46 |
IUPAC Name | 2-Methyl-1-phenyl-4-(2-pyridinyl)-2-[2-(2-pyridinyl)ethyl]-1-butanone |
Synonym | JAK2 inhibitor V, Z3 |
Solubility | Soluble in DMSO or Ethanol |
Store Temp | -20°C |
---|---|
Ship Temp | Ambient |
MSDS | |
---|---|
Info Sheet | |
Brochures |
Sayyah J, Magis A, Ostrov DA, et al. Z3, a novel Jak2 tyrosine kinase small-molecule inhibitor that suppresses Jak2-mediated pathologic cell growth. Mol Cancer Ther. 2008 Aug;7(8):2308-18. PMID: 18723478.
Proteasome inhibitor, miR33b modulator.
GSK3 inhibitor.
Imidzoline derivative; MDM2 inhibitor.
Multikinase inhibitor.
Diterpene found in roasted coffee.
Selective positive allosteric modulator of AMPA...
DNA alkylator.
Abl inhibitor.
Synthetic ITC.
TxA2 synthase inhibitor.
Calcineurin inhibitor.
Src and Abl inhibitor.
Nucleoside (deoxyadenosine) analog found in Co...
Endogenous peptide hormone derived from POMC, i...
Tenoxicam impurity
Cell-penetrating peptide, carries large conjuga...
Synthetic peptide, vasopressin analog; AVPR1 ag...
Oxyindole alkaloid found in Uncaria sinensis; h...
SV2A synaptic vesicle inhibitor.
RT inhibitor.