Description
JAK2 inhibitor V (Z3) is an inhibitor of JAK2 that exhibits anticancer activity. In erythroleukemia cells, this compound induces cell cycle arrest and suppresses cellular proliferation.
| Product Unit Size | Cost | Quantity | Stock |
|---|
JAK2 inhibitor V (Z3) is an inhibitor of JAK2 that exhibits anticancer activity. In erythroleukemia cells, this compound induces cell cycle arrest and suppresses cellular proliferation.
| Cas No. | 195371-52-9 |
|---|---|
| Purity | ≥98% |
| Formula | C23H24N2O |
| Formula Wt. | 344.46 |
| IUPAC Name | 2-Methyl-1-phenyl-4-(2-pyridinyl)-2-[2-(2-pyridinyl)ethyl]-1-butanone |
| Synonym | JAK2 inhibitor V, Z3 |
| Solubility | Soluble in DMSO or Ethanol |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet | |
| Brochures |
Sayyah J, Magis A, Ostrov DA, et al. Z3, a novel Jak2 tyrosine kinase small-molecule inhibitor that suppresses Jak2-mediated pathologic cell growth. Mol Cancer Ther. 2008 Aug;7(8):2308-18. PMID: 18723478.
NSAID; COX-1/2 inhibitor.
Alternaria mycotoxin which may be found in food...
AurKB/C inhibitor.
δ2OR antagonist.
Docetaxel impurity
PARP inhibitor.
PI3K and HDAC inhibitor.
Anthracenedione, DNA intercalator; Pim-1 inhibi...
Flavonoid found in various plant sources; DAT a...
Camptothecin analog; topoisomerase I inhibitor,...
p53 inhibitor
GLP-1 agonist
Mycotoxin produced by species of Aspergillus; D...
Lignan found in Magnolia; GABA-A potentiator.
Insecticide; α-adrenergic agonist, MAO inhibit...
ACE inhibitor.
Snake venom found in Bothrops alternatus urutu....
β-adrenergic agonist.
Acyl transfer catalyst, involved in peptide syn...