Description
Jasplakinolide is a marine toxin that stabilizes actin by inducing polymerization and preventing depolymerization and is used in research models. In animal models, jasplakinolide stimulates follicule growth.
Product Unit Size | Cost | Quantity | Stock |
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Jasplakinolide is a marine toxin that stabilizes actin by inducing polymerization and preventing depolymerization and is used in research models. In animal models, jasplakinolide stimulates follicule growth.
Cas No. | 102396-24-7 |
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Purity | ≥98% |
Formula | C36H45BrN4O6 |
Formula Wt. | 709.68 |
Chemical Name | (4R,7R,10S,13S,15E,17R,19S)-7-[(2-Bromo-1H-indol-3-yl)methyl]-4-(4-hydroxyphenyl)-8,10,13,15,17,19-hexamethyl-1-oxa-5,8,11-triazacyclononadec-15-ene-2,6,9,12-tetrone |
IUPAC Name | (4R,7R,10S,13S,15E,17R,19S)-7-[(2-Bromo-1H-indol-3-yl)methyl]-4-(4-hydroxyphenyl)-8,10,13,15,17,19-hexamethyl-1-oxa-5,8,11-triazacyclononadec-15-ene-2,6,9,12-tetrone |
Synonym | Jaspamide |
Solubility | Soluble in ethanol, methanol or DMSO. |
Appearance | Off-white solid. |
Store Temp | -20°C |
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Ship Temp | Ambient |
MSDS | |
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Info Sheet |
Aida N, Ushikubo T, Kobayashi F, et al. Actin stabilization induces apoptosis in cultured porcine epithelial cell rests of Malassez. Int Endod J. 2015 Jun 27. [Epub ahead of print]. PMID: 26118334.
Cheng Y, Feng Y, Jansson L, et al. Actin polymerization-enhancing drugs promote ovarian follicle growth mediated by the Hippo signaling effector YAP. FASEB J. 2015 Jun;29(6):2423-30. PMID: 25690654.
Schwingshackl A, Roan E, Teng B, et al. TREK-1 Regulates Cytokine Secretion from Cultured Human Alveolar Epithelial Cells Independently of Cytoskeletal Rearrangements. PLoS One. 2015 May 22;10(5):e0126781. PMID: 26001192.
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