LKT Labs

Biochemicals for Life Science Research

Levamisole Hydrochloride

Levamisole Hydrochloride

Product ID L1682
Cas No. 16595-80-5
Purity ≥98%
Product Unit SizeCostQuantityStock
5 g $61.00 In stock
10 g $102.00 In stock
Bulk Quote

Quicklinks

Description

Levamisole is an imidazothiazole that exhibits immunomodulatory, anti-parasitic, anti-helminthic, anti-angiogenic, and anticancer chemotherapeutic activities. Levamisole inhibits alkaline phosphatase and may act as an agonist at nicotinic acetylcholine receptors (nAChRs). In multiple myeloma cells, levamisole induces DNA fragmentation, cytochrome c release and caspase 3 activation, inhibiting cellular proliferation. In other models, levamisole also inhibits proliferation and differentiation of endothelial cells and suppresses growth of various tumors in vivo.

Product Info

Cas No.

16595-80-5
Purity

≥98%
Formula

C11H12N2S • HCl
Formula Wt.

240.76
Chemical Name

Imidazo(2,1-b)thiazole,2,3,5,6-tetrahydro-6-phenyl-, monohydrochloride, (-)- (8CI)

IUPAC Name

(6S)-6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b][1, 3]thiazole;hydrochloride
Synonym

Tetramisole hydrochloride, Citarin L, Ergamisol, Spartakon
Melting Point

228-230°C
Solubility

Soluble in water.

Appearance

A white or almost white crystalline powder

Shipping and Storage

Store Temp

Ambient
Ship Temp

Ambient

Downloads

MSDS

L1682 MSDS PDF
Info Sheet

L1682 Info Sheet PDF

References

Ramanadham M, Nageshwari B. Anti-proliferative effect of levamisole on human myeloma cell lines in vitro. J Immunotoxicol. 2010 Oct-Dec;7(4):327-32. PMID: 20860474.

Friis T, Engel AM, Klein BM, et al. Levamisole inhibits angiogenesis in vitro and tumor growth in vivo. Angiogenesis. 2005;8(1):25-34. PMID: 16132615.

Zinser EW, Wolf ML, Alexander-Bowman SJ, et al. Anthelmintic paraherquamides are cholinergic antagonists in gastrointestinal nematodes and mammals. J Vet Pharmacol Ther. 2002 Aug;25(4):241-50. PMID: 12213111.

Van Belle H. Alkaline phosphatase. I. Kinetics and inhibition by levamisole of purified isoenzymes from humans. Clin Chem. 1976 Jul;22(7):972-6. PMID: 6169.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • T2934

    Thiamphenicol Palmitate

    Chloramphenicol derivative; protein translation...

    ≥98%
  • G0146

    Galanin, human

    Endogenous neuropeptide, involved in nociceptio...

    ≥98%
  • L3250

    D-Limonene

    Terpene found in the rind of various citrus fru...

    ≥97%
  • C4418

    Clemizole Hydrochloride

    TRPC5, NS4B, histamine H1 inhibitor.

    ≥98%
  • D0253

    Danazol

    Ethisterone derivative, synthetic steroid, used...

    ≥99%
  • R2710

    Recombinant Multi-epitope Chimeric HCV Antigen

    Recombinant Multi-epitope Chimeric HCV antigen....

    ≥95%
  • B5871

    Bortezomib

    Proteasome inhibitor.

    ≥98%
  • T564092

    γ-Tocopherol

    Vitamin E component

    ≥98%
  • D022705

    Darunavir

    HIV and AIDS

    ≥99%
  • B3272

    Bis(3,5-dibromosalicyl) Fumarate

    Aspirin analog; hemoglobin chain cross-linker.<...

    ≥91%
  • F5870

    N-formyl-Met-Leu-Phe

    Peptide, involved in neutrophil activation; FPR...

    ≥95%
  • D3447

    Diltiazem Hydrochloride

    Benzothiazepine; L-type Ca2+ channel blocker, p...

    ≥98%
  • T1644

    Telmisartan

    AT-II antagonist, PPARγ/δ modulator.

    ≥98%
  • Q8016

    Quercetin Dihydrate

    Flavonoid found in fruits, vegetables, and grai...

    ≥95%
  • B9700

    BYL719

    p110α PI3K inhibitor.

    ≥99%, ≥99%ee
  • C1609

    Cecropin B

    Antimicrobial peptide found in Hyalophora cecro...

    ≥95%
  • W2933

    WHI-P131

    JAK3 and EGFR inhibitor.

    ≥99%
  • A5302

    Anastrozole

    Aromatase inhibitor.

    ≥99%
  • A6804

    Arbutin

    Glycoside hydroquinone originally found in Berg...

    ≥98%
  • B5875

    Bosutinib, structural isomer

    Bosutinib isomer; Src and Abl inhibitor.

    ≥98%