• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
LY-2874455

LY-2874455

Product ID L9602
Cas No. 1254473-64-7
Purity ≥98%
Product Unit SizeCostQuantityStock
1 mg $168.70 In stock
5 mg $454.20 Please Inquire
10 mg $843.70 Please Inquire
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

LY287445 is an inhibitor of FGFR that exhibits anticancer chemotherapeutic activity. LY287445 inhibits cell proliferation and tumor growth across in vitro and in vivo models of several cancers, including lung cancer, gastric cancer, and multiple myeloma.

Product Info

Cas No.

1254473-64-7

Purity

≥98%

Formula

C21H19Cl2N5O2

Formula Wt.

444.31

IUPAC Name

2-[4-[(E)-2-[5-[(1R)-1-(3,5-dichloropyridin-4-yl)ethoxy]-1H-indazol-3-yl]ethenyl]pyrazol-1-yl]ethanol

Solubility

DMSO 88 mg/mL (198.05 mM) Ethanol 57 mg/mL warmed (128.28 mM) Water Insoluble

Appearance

Off-white Powder

Shipping and Storage

Store Temp

4°C

Ship Temp

Ambient

Downloads

MSDS

L9602 MSDS PDF

Info Sheet

L9602 Info Sheet PDF

References

Zhao G, Li WY, Chen D, et al. A novel, selective inhibitor of fibroblast growth factor receptors that shows a potent broad spectrum of antitumor activity in several tumor xenograft models. Mol Cancer Ther. 2011 Nov;10(11):2200-10. PMID: 21900693.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • S543721

    SNS-032

    Inhibitor of CDK.

    ≥99%
  • I4934

    Imipenem Monohydrate

    Carbapenem β-lactam; penicillin binding protei...

    ≥98%
  • A0934

    Acivicin

    Glutamine analog; γ-glutamyl transferase, CTP ...

    ≥98%
  • H1648

    Hemorphin-7

    Endogenous opioid peptide derived from the β-c...

    ≥95%
  • B3358

    Biochanin A

    Phytoestrogen, flavonoid found in clover, soy, ...

    ≥98%
  • A6982

    Artesunate

    Sesquiterpene lactone derived from Artemesia.

    ≥98%
  • E325127

    EIDD-1931

    Broad-spectrum antiviral activity against SARS-...

    ≥99%
  • D3374

    Disulfiram

    Aldehyde dehydrogenase, 26S proteasome, MGMT in...

    ≥98%
  • R327201

    Rifapentine

    Antibiotic

    ≥97%
  • F465817

    Flunisolide

    Corticosteroid

    ≥90%
  • C6982

    Crustacean Cardioactive Peptide

    Neuropeptide hormone found in arthropods.

    ≥95%
  • P333400

    PIK-75

    p110α inhibitor.

    ≥99%
  • D4802

    17-Dimethylaminoethylamino Demethoxygeldanamycin

    Geldanamycin derivative; HSP90 inhibitor.

    ≥98%
  • H9613

    N-(4-Hydroxyphenyl)retinamide

    Retinol (vitamin A) analog, binds RBP4; Des1 in...

    ≥98%
  • H0169

    Harringtonine

    Cephalotaxine alkaloid originally found in Ceph...

    ≥98%
  • N0123

    Naftopidil

    α1-adrenergic antagonist.

    ≥98%
  • S0072

    5S rRNA modificator

    Electrophile used in 2’-hydroxyl acylation of...

    ≥98%
  • E7758

    Etomidate

    GABA-A agonist.

    ≥99%
  • T0094

    2′,7-Bisacetyltaxol

    Taxane synthesis intermediate.

    ≥96%
  • G681019

    Grapiprant

    EP4 receptor antagonist

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only