• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Monensin Sodium

Monensin Sodium

Product ID M5753
Cas No. 22373-78-0
Purity ≥98%
Product Unit SizeCostQuantityStock
500 mg $66.60 In stock
1 g $95.30 In stock
5 g $334.10 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Monensin is a polyether antibiotic initially produced by Streptomyces that exhibits antibactieral and anti-parasitic activities. Monensin is commercially used in cattle feed; it acts as an ionophore, transporting cations across cell membranes. Monensin inhibits autophagy, interfering with the fusion of the autophagosome and the lysosome.

Product Info

Cas No.

22373-78-0

Purity

≥98%

Formula

C36H61O11 Na

Formula Wt.

692.86

Chemical Name

2-[5-Ethyltetrahydro-5-[tetrahydro-3-methyl-5-[tetra- hydro-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyl- 2H-pyran-2-yl]-2-furyl]-2-furyl]-9-hydroxy-β- methoxy-α,γ,2,8-tetramethyl-1,6-dioxaspiro[4.5]- decane-7-butyric acid sodium salt

IUPAC Name

sodium;(2R,3S,4R)-4-[(2R,5R,7S,8R,9S)-2-[(2R,5S)-5-ethyl-5-[(2S,3R, 5S)-5-[(2S,3S,5R,6R)-6-hydroxy-6-(hydroxymethyl)-3, 5-dimethyloxan-2-yl]-3-methyloxolan-2-yl]oxolan-2-yl]-7-hydroxy-2, 8-dimethyl-1,10-dioxaspiro[4.5]decan-9-yl]-3-methoxy-2-methylpentanoate

Synonym

Monensin sodium salt, Coban, Romemsin, Rumensin

Melting Point

267-269°C

Solubility

Insoluble in water. Soluble in DMSO, ethanol, methanol, chloroform, other organic solvents.

Appearance

A White or Almost White Crystalline Powder

Shipping and Storage

Store Temp

4°C

Ship Temp

Ambient

Downloads

MSDS

M5753 MSDS PDF

Info Sheet

M5753 Info Sheet PDF

References

Choi HS, Jeong EH, Lee TG, et al. Autophagy Inhibition with Monensin Enhances Cell Cycle Arrest and Apoptosis Induced by mTOR or Epidermal Growth Factor Receptor Inhibitors in Lung Cancer Cells. Tuberc Respir Dis (Seoul). 2013 Jul;75(1):9-17. PMID: 23946753.

Lavine MD, Arrizabalaga G. Analysis of monensin sensitivity in Toxoplasma gondii reveals autophagy as a mechanism for drug induced death. PLoS One. 2012;7(7):e42107. PMID: 22848721.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • B5609

    Boc-GRR-AMC

    Peptide, protease substrate.

    ≥98%
  • A0910

    N-Acetyl-S-(N′-phenylthiocarbamoyl)-L-cysteine

    Cysteine-ITC conjugate, antioxidant.

    ≥98%
  • A1592

    ADX-47273

    mGluR5 positive modulator.

    ≥98%
  • T6903

    Tranylcypromine Hydrochloride

    MAO and histone demethylase LSD1 inhibitor.

    ≥98%
  • O9702

    Ozagrel Hydrochloride

    TxA2 synthase inhibitor.

    ≥98%
  • A7204

    AS-605240

    p110δ PI3K inhibitor.

    ≥98%
  • P1764

    Pep-1 Peptide

    Cell-penetrating peptide, carries large conjuga...

    ≥95%
  • R2712

    Recombinant HCV-NS3 Antigens

    Recombinant HCV antigen fragment.

    ≥95%
  • D0260

    DAPT

    γ-Secretase inhibitor.

    ≥98%
  • G3558

    20R-Ginsenoside Rh2

    Triterpene saponin found in Panax.

    ≥98%
  • C8069

    Curcumin

    Diarylheptanoid found in Zingiberaceae.

    ≥97% curcuminoid content
  • M1613

    Medroxyprogesterone 17-Acetate

    Synthetic steroid used in HRT; PR, AR, glucocor...

    ≥99%
  • V0146

    Valsartan

    AT1 inhibitor.

    ≥98%
  • E6783

    R-Equol

    Isoflavone, phytoestrogen found in soy

    ≥98%
  • M1669

    6-Mercaptopurine Monohydrate

    Thiopurine antimetabolite; PRPP amidotransferas...

    ≥98%
  • S8144

    Sulfadoxine

    Sulfonamide; dihydropteroate synthase inhibitor...

    ≥98%
  • N1987

    Neuropeptide Y (13-36), human

    Endogenous peptide neurotransmitter, involved i...

    ≥95%
  • E4417

    Eledoisin Related Peptide

    Peptide, substance P analog; NK agonist.

    ≥95%
  • D0169

    Darifenacin Hydrobromide

    M3 mAChR antagonist.

    ≥98%
  • T3202

    Tianeptine

    μOR and δOR agonist, D2/D3 DA potentiator.

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only