• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
PF-06939999

PF-06939999

Product ID P200099
Cas No. 2159123-14-3
Purity ≥98%
Product Unit SizeCostQuantityStock
1 mg $165.00 In stock
5 mg $353.00 In stock
10 mg $579.00 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

PF-06939999 is a SAM-competitve inhibitor of PRMT5.

Product Info

Cas No.

2159123-14-3

Purity

≥98%

Formula

C22H23F3N4O3

Formula Wt.

448.45

IUPAC Name

(1S,2S,3S,5R)-3-[[6-(difluoromethyl)-5-fluoro-1,2,3,4-tetrahydroisoquinolin-8-yl]oxy]-5-(4-methylpyrrolo[2,3-d]pyrimidin-7-yl)cyclopentane-1,2-diol

Synonym

PF06939999; PRMT5-IN-3

Appearance

White to off white powder

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

Info Sheet

P200099 Info Sheet PDF

References

Jensen-Pergakes K, Tatlock J, Maegley K, et al. SAM-competitive PRMT5 inhibitor PF-06939999 demonstrates antitumor activity in splicing dysregulated NSCLC with decreased liability of drug resistance. Mol Cancer Ther. 2022 Jan;21(1):3-15. PMID 34737197

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • T3454

    Tinidazole

    Nitroimidazole, binds DNA; nucleic acid synthes...

    ≥98%
  • I525138

    Indoximod

    Indoleamine 2,3-dioxygenase inhibitor.

    ≥98%
  • A5161

    Ampiroxicam

    Piroxicam prodrug, NSAID; COX-1/2 inhibitor.

    ≥98%
  • A7618

    Atenolol

    β1-adrenergic antagonist.

    ≥98%
  • C0016

    Caerulomycin A

    Bipyridamine toxin.

    ≥96%
  • L1786

    Levofloxacin Hydrochloride Monohydrate

    Fluoroquinolone, S-(-) isomer of ofloxacin; top...

    ≥90%
  • M1779

    Methyldopa Sesquihydrate

    DOPA decarboxylase inhibitor, indirect α2-adre...

    ≥98%
  • C000170

    C170

    STING inhibitor

    ≥98%
  • R3010

    Recombinant Tp-chimeric protein

    Recombinant chimeric protein containing Trepone...

    ≥95%
  • P4132

    PKI-402

    p110α PI3K and mTOR inhibitor.

    ≥98%
  • G3462

    Ginsenoside F3

    Triterpene saponin found in species of Panax.

    ≥98%
  • P6855

    (±)-S-Propyl-L-cysteine-S-oxide

    Organosulfur found in Allium; analog of alliin....

    ≥98%
  • G4535

    Glimepiride

    Sulfonylurea; ATP-sensitive K+ channel blocker....

    ≥98%
  • A1017

    Aceclofenac

    Diclofenac analog, NSAID; COX-2 inhibitor.

    ≥98%
  • R0348

    Ramelteon

    Melatonin analog; MT1/2 agonist.

    ≥99%
  • N5072

    NMS-1286937

    PLK1 inhibitor.

    ≥98%
  • C3260

    Ciprofibrate

    Fibrate; PPARα agonist.

    ≥98%
  • G4781

    Glucoraphanin Potassium

    Glucosinolate found in cruciferous vegetables.<...

    ≥98%
  • A0820

    N-Acetyl-S-(N′-benzylthiocarbamoyl)-L-cysteine

    Cysteine-ITC conjugate, BITC derivative, antiox...

    ≥98%
  • H9726

    Hygromycin B

    Protein translocation inhibitor.

    ≥95.0%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2026 LKT Laboratories, All Rights Reserved - Products for research use only