Description
PF-06939999 is a SAM-competitve inhibitor of PRMT5.
PF-06939999
Product ID P200099
Cas No. 2159123-14-3
Purity ≥98%
| Product Unit Size | Cost | Quantity | Stock |
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Product Info
| Cas No. | 2159123-14-3 |
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| Purity | ≥98% |
| Formula | C22H23F3N4O3 |
| Formula Wt. | 448.45 |
| IUPAC Name | (1S,2S,3S,5R)-3-[[6-(difluoromethyl)-5-fluoro-1,2,3,4-tetrahydroisoquinolin-8-yl]oxy]-5-(4-methylpyrrolo[2,3-d]pyrimidin-7-yl)cyclopentane-1,2-diol |
| Synonym | PF06939999; PRMT5-IN-3 |
| Appearance | White to off white powder |
Shipping and Storage
| Store Temp | -20°C |
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| Ship Temp | Ambient |
Downloads
| Info Sheet |
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References
Jensen-Pergakes K, Tatlock J, Maegley K, et al. SAM-competitive PRMT5 inhibitor PF-06939999 demonstrates antitumor activity in splicing dysregulated NSCLC with decreased liability of drug resistance. Mol Cancer Ther. 2022 Jan;21(1):3-15. PMID 34737197