LKT Labs

Biochemicals for Life Science Research

PF-06939999

PF-06939999

Product ID P200099
Cas No. 2159123-14-3
Purity ≥98%
Product Unit SizeCostQuantityStock
1 mg $165.40 In stock
5 mg $352.80 In stock
10 mg $578.90 In stock
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Description

PF-06939999 is a SAM-competitve inhibitor of PRMT5.

Product Info

Cas No.

2159123-14-3
Purity

≥98%
Formula

C22H23F3N4O3
Formula Wt.

448.45
IUPAC Name

(1S,2S,3S,5R)-3-[[6-(difluoromethyl)-5-fluoro-1,2,3,4-tetrahydroisoquinolin-8-yl]oxy]-5-(4-methylpyrrolo[2,3-d]pyrimidin-7-yl)cyclopentane-1,2-diol
Synonym

PF06939999; PRMT5-IN-3
Appearance

White to off white powder

Shipping and Storage

Store Temp

-20°C
Ship Temp

Ambient

Downloads

Info Sheet

P200099 Info Sheet PDF

References

Jensen-Pergakes K, Tatlock J, Maegley K, et al. SAM-competitive PRMT5 inhibitor PF-06939999 demonstrates antitumor activity in splicing dysregulated NSCLC with decreased liability of drug resistance. Mol Cancer Ther. 2022 Jan;21(1):3-15. PMID 34737197

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