• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Pyridostatin Trifluoroacetate Salt

Pyridostatin Trifluoroacetate Salt

Product ID P982691
Cas No. 1472611-44-1
Purity ≥95%
Product Unit SizeCostQuantityStock
5 mg $136.30 In stock
10 mg $233.60 In stock
25 mg $532.10 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Pyridostatin trifluoroacetate is a G-quadruplex ligand that induces conformation changes in telomere-G-quadruplex complexes and stimulates double-stranded DNA breakage; it also alters telomere function. Pyridostatin displays antiviral and anticancer activities. In vitro, this compound decreases synthesis of Epstein-Barr virus-encoded nuclear antigen 1. In cancer cells, pyridostatin suppresses cellular viability and growth.

Product Info

Cas No.

1472611-44-1

Purity

≥95%

Formula

C33H33F3N8O7

Formula Wt.

710.67

Chemical Name

4-(2-Aminoethoxy)-N2,N6-bis[4-(2-aminoethoxy)-2-quinolinyl]-2,6-pyridinedicarboxamide trifluoroacetate salt

IUPAC Name

4-(2-aminoethoxy)-2-N,6-N-bis[4-(2-aminoethoxy)quinolin-2-yl]pyridine-2,6-dicarboxamide;2,2,2-trifluoroacetic acid

Synonym

Pyridostatin TFA salt, CCG-270392, Ethyl 4-(4-biphenylyl)-2,7,7-trimethyl-5-oxo-1,4,5,6,7,8-hexahydro-3-quinolinecarboxylate

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

P982691 MSDS PDF

Info Sheet

P982691 Info Sheet PDF

References

Marchand A, Granzhan A, Iida K, et al. Ligand-Induced Conformational Changes with Cation Ejection upon Binding to Human Telomeric DNA G-Quadruplexes. J Am Chem Soc. 2015 Jan 21;137(2):750-6. PMID: 25525863.

Murat P, Zhong J, Lekieffre L, et al. G-quadruplexes regulate Epstein-Barr virus-encoded nuclear antigen 1 mRNA translation. Nat Chem Biol. 2014 May;10(5):358-64. PMID: 24633353.

McLuckie KI, Di Antonio M, Zecchini H, et al. G-quadruplex DNA as a molecular target for induced synthetic lethality in cancer cells. J Am Chem Soc. 2013 Jul 3;135(26):9640-3. PMID: 23782415.

Müller S, Sanders DA, Di Antonio M, et al. Pyridostatin analogues promote telomere dysfunction and long-term growth inhibition in human cancer cells. Org Biomol Chem. 2012 Aug 28;10(32):6537-46. PMID: 22790277.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • A7462

    Aspartame

    Dipeptide ester, commercial sweetener.

    ≥98%
  • Y4800

    YM-155

    Survivin inhibitor.

    ≥99%
  • D1746

    Deltarasin Hydrochloride Trihydrate

    PDEδ inhibitor.

    ≥99%
  • F5773

    Fosinopril Sodium

    ACE inhibitor.

    ≥98%
  • P2400

    Phenethyl Caffeate

    Found in propolis; 5-lipoxygenase inhibitor.

    ≥98%
  • A4646

    ALLN

    Calpain I/II inhibitor.

    ≥98%
  • M1626

    Megestrol Acetate

    Synthetic progestogen, orexigenic.

    ≥98%
  • L3561

    D,L-α-Lipoic Acid

    Endogenous organosulfur also found in meat and ...

    ≥99%
  • P9671

    Pyrazinamide

    Nicotinamide analog prodrug; fatty acid synthet...

    ≥98%
  • C2961

    Chondroitin Sulfate, chicken

    Polyanionic sulfated glycosaminoglycan, endogen...

    ≥90%
  • U0618

    Ubenimex

    Dipeptide; aminopeptidase (N/CD13) inhibitor.

    ≥98%
  • P5745

    Polygalic Acid

    Saponin found in Polygala.

    ≥97%
  • T0008

    Tacrolimus

    Calcineurin inhibitor.

    ≥98%
  • L1628

    Ac-LEHD-pNa

    Caspase 9 substrate.

    ≥95%
  • N3422

    Nifekalant Hydrochloride

    Voltage-gated K+ channel blocker.

    ≥98%
  • D3215

    Didymin

    Flavonoid glycoside found in citrus fruit.

    ≥98%
  • I7556

    1-Isothiocyanato-7-(methylsulfonyl)-heptane

    ITC, erysolin analog.

    ≥98%
  • B5044

    BML-277

    Arylbenzimidazole; CHK2 inhibitor.

    ≥98%
  • M3309

    Miconazole

    Imidazole; 14-α demethylase inhibitor, potenti...

    ≥98%
  • A3080

    AHU-377 Tris Salt

    LBQ657 prodrug; neprilysin inhibitor.

    ≥99%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only