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Ramipril

Ramipril

Product ID R0249
Cas No. 87333-19-5
Purity ≥98%
Product Unit SizeCostQuantityStock
100 mg $67.80 In stock
500 mg $127.90 In stock
1 g $225.40 In stock
5 g $631.20 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Ramipril is an angiotensin-converting enzyme (ACE) inhibitor that exhibits anti-arrhythmic, antihypertensive, and cardioprotective activities. In animal models of myocardial infarction, ramipril decreases ventricular tachycardia and ventricular fibrillation. In other, similar animal models, ramipril increases antioxidative enzyme activity, improving left ventricular ejection fraction and inhibiting left ventricular remodeling. Ramipril is clinically used to treat high blood pressure, congestive heart failure (CHF), and diabetic neuropathy.

Product Info

Cas No.

87333-19-5

Purity

≥98%

Formula

C23H32N2O5

Formula Wt.

416.51

Chemical Name

[2S,3aS,6aS]-1-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)-3- phenylpropyl]amino]-1-oxopropyl]octahydrocyclo- penta[b]pyrrole-2-carboxylic acid

IUPAC Name

(2S,3aS, 6aS)-1-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl] -3,3a,4,5,6,6a-hexahydro-2H-cyclopenta[b]pyrrole-2-carboxylic acid

Synonym

Tritace, Ramace, Unipril, Vesdil

Melting Point

109°C

Solubility

Soluble in DMSO (10mg/mL).and Acetonitrile

Appearance

White Crystal Powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

R0249 MSDS PDF

Info Sheet

R0249 Info Sheet PDF

References

Zhong Y, Cao P, Tong C, et al. Effect of ramipril on the electrophysiological characteristics of ventricular myocardium after myocardial infarction in rabbits. J Cardiovasc Med (Hagerstown). 2012 May;13(5):313-8. PMID: 22441218.

Chen CY, Lee BC, Hsu HC, et al. A proteomic study of the effects of ramipril on post-infarction left ventricular remodelling in the rabbit. Eur J Heart Fail. 2008 Aug;10(8):740-8. PMID: 18583185.

Dupuis F, Atkinson J, Limiñana P, et al. Comparative effects of the angiotensin II receptor blocker, telmisartan, and the angiotensin-converting enzyme inhibitor, ramipril, on cerebrovascular structure in spontaneously hypertensive rats. J Hypertens. 2005 May;23(5):1061-6. PMID: 15834293.

Custom Order

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