LKT Labs

Biochemicals for Life Science Research

Ramipril

Ramipril

Product ID R0249
Cas No. 87333-19-5
Purity ≥98%
Product Unit SizeCostQuantityStock
100 mg $68.00 In stock
500 mg $128.00 In stock
1 g $225.00 In stock
5 g $631.00 In stock
Bulk Quote

Quicklinks

Description

Ramipril is an angiotensin-converting enzyme (ACE) inhibitor that exhibits anti-arrhythmic, antihypertensive, and cardioprotective activities. In animal models of myocardial infarction, ramipril decreases ventricular tachycardia and ventricular fibrillation. In other, similar animal models, ramipril increases antioxidative enzyme activity, improving left ventricular ejection fraction and inhibiting left ventricular remodeling. Ramipril is clinically used to treat high blood pressure, congestive heart failure (CHF), and diabetic neuropathy.

Product Info

Cas No.

87333-19-5
Purity

≥98%
Formula

C23H32N2O5
Formula Wt.

416.51
Chemical Name

[2S,3aS,6aS]-1-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)-3- phenylpropyl]amino]-1-oxopropyl]octahydrocyclo- penta[b]pyrrole-2-carboxylic acid
IUPAC Name

(2S,3aS, 6aS)-1-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl] -3,3a,4,5,6,6a-hexahydro-2H-cyclopenta[b]pyrrole-2-carboxylic acid
Synonym

Tritace, Ramace, Unipril, Vesdil
Melting Point

109°C
Solubility

Soluble in DMSO (10mg/mL).and Acetonitrile
Appearance

White Crystal Powder

Shipping and Storage

Store Temp

Ambient
Ship Temp

Ambient

Downloads

MSDS

R0249 MSDS PDF
Info Sheet

R0249 Info Sheet PDF

References

Zhong Y, Cao P, Tong C, et al. Effect of ramipril on the electrophysiological characteristics of ventricular myocardium after myocardial infarction in rabbits. J Cardiovasc Med (Hagerstown). 2012 May;13(5):313-8. PMID: 22441218.

Chen CY, Lee BC, Hsu HC, et al. A proteomic study of the effects of ramipril on post-infarction left ventricular remodelling in the rabbit. Eur J Heart Fail. 2008 Aug;10(8):740-8. PMID: 18583185.

Dupuis F, Atkinson J, Limiñana P, et al. Comparative effects of the angiotensin II receptor blocker, telmisartan, and the angiotensin-converting enzyme inhibitor, ramipril, on cerebrovascular structure in spontaneously hypertensive rats. J Hypertens. 2005 May;23(5):1061-6. PMID: 15834293.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • I2056

    Ifosfamide

    Nitrogen mustard, DNA alkylator.

    ≥98%
  • V5254

    Vincristine Sulfate

    Vinca alkaloid found in Catharanthus; microtubu...

    ≥98%
  • L8377

    Luteolin

    Flavonoid found in various plant sources; DAT a...

    ≥95%
  • A2077

    Afatinib

    EGFR inhibitor.

    ≥98%
  • P7023

    Pregnenolone

    Endogenous precursor to all steroid hormones; T...

    ≥98%
  • D183744

    Destruxin A

    Cyclic depsipeptide is a secondary metabolite i...

    ≥98%
  • C2970

    Chrysophanol

    Anthraquinone found in Rheum.

    ≥98%
  • C4558

    Clonidine Hydrochloride

    Imidazoline and α2-adrenergic agonist, Nav1.7 ...

    ≥98%
  • P2502

    Phenethyl Glucosinolate Potassium

    Found in cruciferous vegetables.

    ≥97%
  • G5216

    GNE-7915

    LRRK2 inhibitor.

    ≥98%
  • P7218

    Pseudoprotodioscin

    Steroidal saponin found in Tribulus, Trigonella...

    ≥98%
  • B1653

    Benzyl Isothiocyanate

    ITC found in cruciferous vegetables.

    ≥99%
  • A4847

    Amylin, human

    Endogenous peptide hormone inolved in gastric e...

    ≥95%
  • R3577

    Ritonavir

    HIV protease inhibitor.

    ≥98%
  • S1845

    L-(+)-Selenomethionine

    Naturally occurring amino acid found in grains,...

    ≥98%
  • A851322

    Avibactam Sodium

    Diazabicyclooctane β-lactamase inhibitor.

    ≥98%
  • P2410

    Phenethyl Dimethyl Caffeate

    Caffeic acid derivative.

    ≥98%
  • I0480

    Ibudilast

    PDE3/5 inhibitor, LTD4 antagonist.

    ≥98%
  • P0397

    Pazopanib

    VEGFR, PDGFR, c-Kit inhibitor.

    ≥97%
  • D3202

    Diallyl Trisulfide

    Organosulfur found in garlic.

    ≥98%