LKT Labs

Biochemicals for Life Science Research

Ramipril

Ramipril

Product ID R0249
Cas No. 87333-19-5
Purity ≥98%
Product Unit SizeCostQuantityStock
100 mg $67.80 In stock
500 mg $127.90 In stock
1 g $225.40 In stock
5 g $631.20 In stock
Bulk Quote

Quicklinks

Description

Ramipril is an angiotensin-converting enzyme (ACE) inhibitor that exhibits anti-arrhythmic, antihypertensive, and cardioprotective activities. In animal models of myocardial infarction, ramipril decreases ventricular tachycardia and ventricular fibrillation. In other, similar animal models, ramipril increases antioxidative enzyme activity, improving left ventricular ejection fraction and inhibiting left ventricular remodeling. Ramipril is clinically used to treat high blood pressure, congestive heart failure (CHF), and diabetic neuropathy.

Product Info

Cas No.

87333-19-5
Purity

≥98%
Formula

C23H32N2O5
Formula Wt.

416.51
Chemical Name

[2S,3aS,6aS]-1-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)-3- phenylpropyl]amino]-1-oxopropyl]octahydrocyclo- penta[b]pyrrole-2-carboxylic acid
IUPAC Name

(2S,3aS, 6aS)-1-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl] -3,3a,4,5,6,6a-hexahydro-2H-cyclopenta[b]pyrrole-2-carboxylic acid
Synonym

Tritace, Ramace, Unipril, Vesdil
Melting Point

109°C
Solubility

Soluble in DMSO (10mg/mL).and Acetonitrile
Appearance

White Crystal Powder

Shipping and Storage

Store Temp

Ambient
Ship Temp

Ambient

Downloads

MSDS

R0249 MSDS PDF
Info Sheet

R0249 Info Sheet PDF

References

Zhong Y, Cao P, Tong C, et al. Effect of ramipril on the electrophysiological characteristics of ventricular myocardium after myocardial infarction in rabbits. J Cardiovasc Med (Hagerstown). 2012 May;13(5):313-8. PMID: 22441218.

Chen CY, Lee BC, Hsu HC, et al. A proteomic study of the effects of ramipril on post-infarction left ventricular remodelling in the rabbit. Eur J Heart Fail. 2008 Aug;10(8):740-8. PMID: 18583185.

Dupuis F, Atkinson J, Limiñana P, et al. Comparative effects of the angiotensin II receptor blocker, telmisartan, and the angiotensin-converting enzyme inhibitor, ramipril, on cerebrovascular structure in spontaneously hypertensive rats. J Hypertens. 2005 May;23(5):1061-6. PMID: 15834293.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • T0250

    Tamoxifen Citrate

    4-Hydroxytamoxifen prodrug; FIASMA, SERM, PKC i...

    ≥98%
  • H9726

    Hygromycin B

    Protein translocation inhibitor.

    ≥95.0%
  • A4617

    Aloe Emodin

    Anthraquinone found in aloe; CTFR Cl- channel a...

    ≥98%
  • P1754

    Penciclovir

    Nucleoside (guanosine) analog; DNA chain termin...

    ≥98%
  • M184790

    Metyrapone

    Steroidogenesis inhibitor

    ≥98%
  • C1613

    Cediranib

    VEGFR inhibitor.

    ≥98%
  • D4802

    17-Dimethylaminoethylamino Demethoxygeldanamycin

    Geldanamycin derivative; HSP90 inhibitor.

    ≥98%
  • S7868

    SRT1720 Hydrochloride

    SIRT 1 activator, SIRT3 inhibitor.

    ≥98%
  • A4444

    L-Alliin

    Cysteine derivative found in Allium; NMDA NR2A/...

    ≥98%
  • A9600

    AZD-3463

    ALK and IGF-1R inhibitor.

    ≥99%
  • S7618

    StemRegenin 1 Hydrochloride

    AhR antagonist.

    ≥98%
  • D564088

    10-Acetyl Docetaxel

    Docetaxel impurity

    ≥98%
  • T4800

    TM3-0089 Sodium Monohydrate

    CRTH2 inhibitor.

    ≥98%
  • R3475

    Risperidone

    Benzisoxazole; 5-HT7 and NMDA agonist, D-amino ...

    ≥98%
  • T2817

    Theophylline

    Methylxanthine; PDE inhibitor, A1/2 adenosine a...

    ≥98%
  • R2714

    Recombinant HCV-NS5 Antigens

    Recombinant HCV antigen fragment.

    ≥95%
  • D6108

    1,4-DPCA

    Prolyl hydroxylase inhibitor.

    ≥98%
  • D1774

    Desloratadine

    Loratadine metabolite; FIASMA, histamine H1 ant...

    ≥97%
  • V0160

    Vapreotide

    Synthetic somatostatin analog, peptide; somatos...

    ≥95%
  • C2942

    Mechlorethamine Hydrochloride

    Nitrogen mustard, DNA alkylator.

    ≥98%