LKT Labs

Biochemicals for Life Science Research

Ramipril

Ramipril

Product ID R0249
Cas No. 87333-19-5
Purity ≥98%
Product Unit SizeCostQuantityStock
100 mg $67.80 In stock
500 mg $127.90 In stock
1 g $225.40 In stock
5 g $631.20 In stock
Bulk Quote

Quicklinks

Description

Ramipril is an angiotensin-converting enzyme (ACE) inhibitor that exhibits anti-arrhythmic, antihypertensive, and cardioprotective activities. In animal models of myocardial infarction, ramipril decreases ventricular tachycardia and ventricular fibrillation. In other, similar animal models, ramipril increases antioxidative enzyme activity, improving left ventricular ejection fraction and inhibiting left ventricular remodeling. Ramipril is clinically used to treat high blood pressure, congestive heart failure (CHF), and diabetic neuropathy.

Product Info

Cas No.

87333-19-5
Purity

≥98%
Formula

C23H32N2O5
Formula Wt.

416.51
Chemical Name

[2S,3aS,6aS]-1-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)-3- phenylpropyl]amino]-1-oxopropyl]octahydrocyclo- penta[b]pyrrole-2-carboxylic acid
IUPAC Name

(2S,3aS, 6aS)-1-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl] -3,3a,4,5,6,6a-hexahydro-2H-cyclopenta[b]pyrrole-2-carboxylic acid
Synonym

Tritace, Ramace, Unipril, Vesdil
Melting Point

109°C
Solubility

Soluble in DMSO (10mg/mL).and Acetonitrile
Appearance

White Crystal Powder

Shipping and Storage

Store Temp

Ambient
Ship Temp

Ambient

Downloads

MSDS

R0249 MSDS PDF
Info Sheet

R0249 Info Sheet PDF

References

Zhong Y, Cao P, Tong C, et al. Effect of ramipril on the electrophysiological characteristics of ventricular myocardium after myocardial infarction in rabbits. J Cardiovasc Med (Hagerstown). 2012 May;13(5):313-8. PMID: 22441218.

Chen CY, Lee BC, Hsu HC, et al. A proteomic study of the effects of ramipril on post-infarction left ventricular remodelling in the rabbit. Eur J Heart Fail. 2008 Aug;10(8):740-8. PMID: 18583185.

Dupuis F, Atkinson J, Limiñana P, et al. Comparative effects of the angiotensin II receptor blocker, telmisartan, and the angiotensin-converting enzyme inhibitor, ramipril, on cerebrovascular structure in spontaneously hypertensive rats. J Hypertens. 2005 May;23(5):1061-6. PMID: 15834293.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • O6805

    Orbifloxacin

    Fluoroquinolone; bacterial DNA gyrase inhibitor...

    ≥99%
  • S801001

    SU-5402

    Inhibitor of VEGFR and FGFR.

    ≥98%
  • P327212

    Pifithrin-α-cyclic Hydrobromide

    p53 inhibitor

    ≥98%
  • P2919

    L-Phenylalaninol

    Non-essential amino acid alcohol.

    ≥98%
  • T1853

    Tenovin-6

    SIRT1/2 inhibitor, indirect p53 activator.

    ≥98%
  • K5606

    Kobe 2602

    Ras inhibitor.

    ≥98%
  • E6234

    Epigallocatechin Gallate

    Flavanol found in Camilla (green tea); AhR ant...

    ≥98%
  • P982691

    Pyridostatin Trifluoroacetate Salt

    G-quadruplex ligand; DNA breakage inducer.

    ≥95%
  • F4679

    Flubendazole

    Benzimidazole; microtubule polymerization inhib...

    ≥98%
  • S1058

    Scopolamine N-butylbromide

    Tropane alkaloid found in Solanaceae plants; M1...

    ≥98%
  • D3261

    Dipropyl Disulfide

    Organosulfide found in Allium; cholesterol synt...

    ≥99%
  • A5033

    4-Aminosalicylic Acid

    Dihydrofolate reductase inhibitor.

    ≥98%
  • P6004

    PP-242

    Dual mTORC1/mTORC2 inhibitor.

    ≥98%
  • H1672

    Hesperetin

    Flavanone found in species of Citrus; L-type Ca...

    ≥97%
  • P8382

    Puupehenone

    Sesquiterpene found in marine sponges.

    ≥94%
  • T2970

    Thrombin Receptor Agonist Peptide

    Peptide; PAR1 agonist.

    ≥95%
  • L960008

    LY-3177833

    Cdc7 inhibitor.

    ≥99%
  • T0298

    Tazobactam

    β-lactamase inhibitor.

    ≥98%
  • T2934

    Thiamphenicol Palmitate

    Chloramphenicol derivative; protein translation...

    ≥98%
  • V1810

    Vecuronium Bromide

    Non-depolarizing NMJ blocker; nAChR antagonist....

    ≥98%