LKT Labs

Biochemicals for Life Science Research

RFRP-1, human

RFRP-1, human

Product ID R2369
Cas No.
Purity ≥95%
Product Unit SizeCostQuantityStock
0.5 mg $98.40 Please Inquire
1 mg $166.80 Please Inquire
2.5 mg $294.60 Please Inquire
Bulk Quote

Quicklinks

Description

RFRP-1 is a mammalian ortholog of avian gonadotropin inhibitory hormone (GnIH). RFRP-1 and other RF-amide family peptides activate their own receptor, GPR147. RFRP-1 exhibits anorexigenic, anti-fertility, and anxiogenic activities. RFRP-1-secreting neurons are stress activated and inhibit the secretion of gonadotropin and gonadotropin-releasing hormone (GnRH). In vivo, this peptide inhibits reproductive behavior, decreases food intake, and increases anxiety behavior in an oxytocin-mediated manner.

Product Info

Purity

≥95%
Formula

C67H101N19O14S
Formula Wt.

1428.73
Synonym

RF amide-related peptide-1, Neuropeptide VF precursor.
Solubility

Soluble in water.

Shipping and Storage

Store Temp

-20°C
Ship Temp

Ambient

Downloads

MSDS

R2369 MSDS PDF
Info Sheet

R2369 Info Sheet PDF

References

Kovács A, László K, Gálosi R, et al. Microinjection of RFRP-1 in the central nucleus of amygdala decreases food intake in the rat. Brain Res Bull. 2012 Sep 1;88(6):589-95. PMID: 22691952.

Kaewwongse M, Takayanagi Y, Onaka T. Effects of RFamide-related peptide (RFRP)-1 and RFRP-3 on oxytocin release and anxiety-related behaviour in rats. J Neuroendocrinol. 2011 Jan;23(1):20-7. PMID: 21029217.

Clarke IJ, Qi Y, Puspita Sari I, et al. Evidence that RF-amide related peptides are inhibitors of reproduction in mammals. Front Neuroendocrinol. 2009 Aug;30(3):371-8. PMID: 19362107.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • V3253

    Vinblastine Sulfate

    Vinca alkaloid found in Catharanthus; microtubu...

    ≥96%
  • B8277

    Butein

    Flavonoid found in Rhus verniciflua and Butea m...

    ≥99%
  • F4680

    Flutamide

    Non-steroid; AR antagonist.

    ≥98%
  • C0800

    C59

    PORCN inhibitor.

    ≥98%
  • A6827

    Argipressin Acetate

    Endogenous peptide, involved in vascular contra...

    ≥95%
  • P1200

    PD-184352

    MEK1/2 and Raf inhibitor.

    ≥98%
  • V3378

    Vitamin B12

    Coenzyme, vitamin found in dairy, meat, eggs, f...

    ≥97%
  • A0971

    Adrenocorticotropic Hormone (4-10), human

    Endogenous peptide hormone fragment, involved i...

    ≥95%
  • P2510

    4-Phenylbutylisothiocyanate

    Synthetic ITC.

    ≥98%
  • T286165

    Theaflavin-3-gallate

    Polyphenolic compound present in black tea.

    ≥95%
  • S6000

    Sparfloxacin

    Fluoroquinolone; topoisomerase IV and bacterial...

    ≥98%
  • E7329

    Ethoxyquin

    Quinoline, food preservative; HSP90 inhibitor.<...

    ≥90%
  • D0253

    Danazol

    Ethisterone derivative, synthetic steroid, used...

    ≥99%
  • O1177

    n-Octyl-3,4-Dimethylcaffeate

    Methylated derivative of n-octyl-caffeate.

    ≥98%
  • J889290

    JWH 133

    Cannabinoid receptor 2 selective agonist.

    ≥95%
  • U698576

    Urolithin B

    Ellagic acid derivative produced by gut microfl...

    ≥99%
  • E5210

    Endomorphin-1

    Endogenous opioid peptide; μOr agonist.

    ≥95%
  • E7578

    Estramustine

    Nitrogen mustard and estradiol derivative; micr...

    ≥97%
  • O0977

    Octopamine Hydrochloride

    Endogenous biogenic amine, norepinephrine-like ...

    ≥98%
  • A0965

    Adrenocorticotropic Hormone (1-14)

    Endogenous peptide hormone fragment, involved i...

    ≥95%