Description
RGD is a peptide that delivers attached compounds to targets such as thrombus or tumor cells; it enhances efficacy of anticancer and anti-aggregation or anti-adhesion compounds. RDG binds integrins on the surfaces of cells.
RGD
Product ID R2512
Cas No. 99896-85-2
Purity ≥95%
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Product Info
| Cas No. | 99896-85-2 |
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| Purity | ≥95% |
| Formula | C12H22N6O6 |
| Formula Wt. | 346.3 |
| Chemical Name | Arginyl-glycyl-aspartic acid |
| IUPAC Name | (2S)-2-[[2-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino] acetyl]amino]butanedioic acid |
| Solubility | Soluble in water (10 mg/mL). Insoluble in ethanol, DMSO. |
| Appearance | White to off white powder |
Shipping and Storage
| Store Temp | -20°C |
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| Ship Temp | Ambient |
Downloads
| MSDS | |
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| Info Sheet |
References
Guo Z, He B, Jin H, et al. Targeting efficiency of RGD-modified nanocarriers with different ligand intervals in response to integrin αvβ3 clustering. Biomaterials. 2014 Apr 30. [Epub ahead of print]. PMID: 24794924.
Li Y, Zheng X, Sun Y, et al. RGD-fatty alcohol-modified docetaxel liposomes improve tumor selectivity in vivo. Int J Pharm. 2014 Apr 4;468(1-2):133-141. [Epub ahead of print]. PMID: 24709214.
Zhao M, Wang C, Jiang X, et al. Synthesis of RGD containing peptides and their bioactivities. Prep Biochem Biotechnol. 2002 Nov;32(4):363-80. PMID: 12455829.
Preferred conformations of RGDX tetrapeptides to inhibit the binding of fibrinogen to platelets.
Park HS, Kim C, Kang YK. Biopolymers. 2002 Apr 15;63(5):298-313. PMID: 11877740.