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Ritodrine Hydrochloride

Ritodrine Hydrochloride

Product ID R3477
Cas No. 23239-51-2
Purity ≥98%
Product Unit SizeCostQuantityStock
250 mg $84.30 In stock
1 g $240.10 In stock
5 g $506.20 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
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  • References
  • Description
  • Product Info
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Description

Ritodrine is a β2-adrenergic receptor agonist that exhibits tocolytic activity. Ritodrine is clinically used to prevent preterm labor, as it decreases prostanoid signaling and inhibits uterine contractility. Ritodrine activates Ca2+-activated (SK/BK) K+ channels and ATP-sensitive K+ channels, potentially underlying its smooth muscle cell relaxant effects. Additionally, ritodrine may induce the formation of pruritic erythematous papular eruptions when used clinically.

Product Info

Cas No.

23239-51-2

Purity

≥98%

Formula

C17H21NO3 • HCl

Formula Wt.

323.82

IUPAC Name

4-[2-[[(1R, 2S)-1-hydroxy-1-(4-hydroxyphenyl)propan-2-yl]amino]ethyl]phenol; hydrochloride

Synonym

Ritodrina, Ritodrinium

Melting Point

192-196°C

Appearance

White to Yellow Powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

R3477 MSDS PDF

Info Sheet

R3477 Info Sheet PDF

References

Sato Y, Teraki Y, Izaki S, et al. Ritodrine-induced erythematous papular eruption in 14 pregnant women. Int J Dermatol. 2010 Dec;49(12):1450-3. PMID: 21091685.

Schwarz MK, Page P. Preterm labour: an overview of current and emerging therapeutics. Curr Med Chem. 2003 Aug;10(15):1441-68. PMID: 12871140.

Hamada Y, Nakaya Y, Hamada S, et al. Activation of K+ channels by ritodrine hydrochloride in uterine smooth muscle cells from pregnant women. Eur J Pharmacol. 1994 Dec 15;288(1):45-51. PMID: 7705467.

Dubin NH, Ghodgaonkar RB. Effect of ritodrine hydrochloride and dibutyryl cyclic AMP on contractile activity and prostanoid production of uteri from pregnant rats in vitro. Prostaglandins Leukot Med. 1984 Feb;13(2):119-28. PMID: 6326162.

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