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Sparfloxacin

Sparfloxacin

Product ID S6000
Cas No. 110871-86-8
Purity ≥98%
Product Unit SizeCostQuantityStock
500 mg $50.90 In stock
1 g $81.70 In stock
5 g $255.30 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Sparfloxacin is a fluoroquinolone antibiotic that is clinically used to treat respiratory infections; it displays antibacterial efficacy by inhibiting DNA gyrase and topoisomerase IV. Gold(III)-chelated sparfloxacin inhibits proliferation of lymphoma, leukemia, melanoma, and lung cancer cells, displaying anticancer activity.

Product Info

Cas No.

110871-86-8

Purity

≥98%

Formula

C19H22F2N4O3

Formula Wt.

392.40 g/mol

Chemical Name

rel-5-Amino-1-cyclopropyl-7-[(3R,5S)-3,5-dimethyl-1-piperazinyl]-6,8-difluoro-1,4-dihydro-4-oxo-3- quinolinecarboxylic acid

IUPAC Name

5-amino-1-cyclopropyl-7-[(3S,5R)-3,5-dimethylpiperazin-1-yl]-6, 8-difluoro-4-oxoquinoline-3-carboxylic acid

Synonym

Zagam, Spara

Melting Point

266-269°C

Solubility

Soluble in alcohol and chloroform. Water(0.11 g/100 ml)

Appearance

Yellow crystalline powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

S6000 MSDS PDF

Info Sheet

S6000 Info Sheet PDF

References

Gouvea LR, Garcia LS, Lachter DR, et al. Atypical fluoroquinolone gold(III) chelates as potential anticancer agents: relevance of DNA and protein interactions for their mechanism of action. Eur J Med Chem. 2012 Sep;55:67-73. PMID: 22835721.

Harding I, Simpson I. Fluoroquinolones: is there a different mechanism of action and resistance against Streptococcus pneumoniae? J Chemother. 2000 Oct;12 Suppl 4:7-15. PMID: 11131958.

Schentag JJ. Sparfloxacin: a review. Clin Ther. 2000 Apr;22(4):372-87; PMID: 10823360.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

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