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Tedizolid Phosphate

Tedizolid Phosphate

Product ID T165133
Cas No. 856867-55-5
Purity ≥98%
Product Unit SizeCostQuantityStock
5 mg $120.80 In stock
25 mg $362.30 In stock
100 mg $892.50 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Tedizolid is a second-generation oxazolidinone found to be effective against gram-positive pathogens. In murine models of penicillin-resistant Streptococcus pneumoniae infection, tedizolid was as effective as or more effective than linezolid and showed less inflammatory cell invasion into alveolar spaces. In another study on a murine model of hematogenous pulmonary infection, tedizolid and linezolid both showed antimicrobial and immunomodulatory results superior to treatment with vancomycin.

Product Info

Cas No.

856867-55-5

Purity

≥98%

Formula

C17H16FN6O6P

Formula Wt.

450.32

Chemical Name

(R)-(3-(3-fluoro-4-(6-(2-methyl-2H-tetrazol-5-yl)pyridin-3-yl)phenyl)-2-oxooxazolidin-5-yl)methyl dihydrogen phosphate

IUPAC Name

[(5R)-3-[3-fluoro-4-[6-(2-methyltetrazol-5-yl)pyridin-3-yl]phenyl]-2-oxo-1,3-oxazolidin-5-yl]methyl dihydrogen phosphate

Synonym

DA 7218, Sivextro, TR 701

Solubility

Soluble in DMSO

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

T165133 MSDS PDF

Info Sheet

T165133 Info Sheet PDF

References

Choi S, Im W, Bartizal K. Activity of tedizolid phosphate (TR-701) in murine models of infection with penicillin-resistant and penicillin-sensitive Streptococcus pneumoniae. Antimicrob Agents Chemother. 2012 Sep;56(9):4713-4717. PMID: 22713339.

Kaku N, Morinaga Y, Takeda K, et al. Antimicrobial and immunomodulatory effects of tedizolid against methicillin-resistant Staphylococcus aureus in a murine model of hematogenous pulmonary infection. Int J Med Microbiol. 2016 Sep;306(6):421-428. PMID: 27259840.

Park KH, Greenwood-Quaintance KE, Mandrekar J, et al. Activity of tedizolid in methicillin-resistant Staphylococcus aureus experimental foreign body-associated osteomyelitis. Antimicrob Agents Chemother. 2016 Oct 21;60(11):6568-6572. PMID: 27550347.

Custom Order

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