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Vanilloid Receptor 1 Fragment

Product ID V0153
Cas No.
Purity ≥95%
Product Unit SizeCostQuantityStock
1 mg $237.70 Please Inquire
2 mg $404.40 Please Inquire
5 mg $712.10 Please Inquire
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  • Product Info
  • Shipping and Storage
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  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
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Description

Transient receptor potential vanilloid 1 (TRPV1) channels are activated by heat, proton, endovanilloids, endocannabinoids, and inflammatory mediators. TRPV1 is also considered the capsaicin receptor; it modulates neurotransmission and pain/nociceptive signaling. TRPV1 is expressed on neurons in arteries, blood vessels, skin tissues, and in the brain. Activation of TRPV1 may result in skeletal muscle constriction and arterial vasoconstriction.

Product Info

Purity

≥95%

Formula

C75H118N18O28S2

Formula Wt.

1783.99

Synonym

Transient receptor potential vanilloid 1, TRPV1, VR1, capsaicin receptor, Vanilloid Receptor Subtype 1

Appearance

White to off white powder

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

V0153 MSDS PDF

Info Sheet

V0153 Info Sheet PDF

References

Anwar IJ, Derbenev AV. TRPV1-dependent regulation of synaptic activity in the mouse dorsal motor nucleus of the vagus nerve. Front Neurosci. 2013 Dec 13;7:238. PMID: 24379754.

Tóth A, Czikora A, Pásztor ET, et al. Vanilloid Receptor-1 (TRPV1) Expression and Function in the Vasculature of the Rat. J Histochem Cytochem. 2013 Dec 5. [Epub ahead of print]. PMID: 24217926.

Kelly S, Chapman RJ, Woodhams S, et al. Increased function of pronociceptive TRPV1 at the level of the joint in a rat model of osteoarthritis pain. Ann Rheum Dis. 2013 Oct 23. [Epub ahead of print]. PMID: 24152419.

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