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Vecuronium is a non-depolarizing muscle relaxant that inhibits nicotinic acetylcholine receptors (nAChRs), blocking neurotransmission at the neuromuscular junction. Vecuronium is clinically used as an anesthetic and paralytic during tracheal intubation.
| Cas No. | 50700-72-6 |
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| Purity | ≥98% |
| Formula | C34H57BrN2O4 |
| Formula Wt. | 637.74 |
| Chemical Name | 1-[(2α,3β5α,16β,17β)-3,17-Bis(acetyloxy)-2-(1- piperidinyl)androstan-16-yl]-1-methylpiperidinium bromide |
| IUPAC Name | [(2S,3S,5S,8R,9S,10S,13S,14S,16S,17R)-17-acetyloxy-10,13-dimethyl-16-(1-methylpiperidin-1-ium-1-yl)-2-piperidin-1-yl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl] acetate;bromide |
| Synonym | Musculax, Norcuron, NC-45, Org-NC-45 |
| Melting Point | 227-229°C |
| Solubility | Soluble in water, DMSO, ethanol, chloroform, methanol. |
| Appearance | White or almost white crystal powder |
| Store Temp | -20°C |
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| Ship Temp | Ambient |
| MSDS | |
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| Info Sheet |
de Boer HD. Neuromuscular transmission: new concepts and agents. J Crit Care. 2009 Mar;24(1):36-42. PMID: 19272537.
Jonsson M, Gurley D, Dabrowski M, et al. Distinct pharmacologic properties of neuromuscular blocking agents on human neuronal nicotinic acetylcholine receptors: a possible explanation for the train-of-four fade. Anesthesiology. 2006 Sep;105(3):521-33. PMID: 16931985.