Description
Flumazenil is an antagonist at GABA-A receptors that is used as a stimulant to counteract the effects of benzodiazepines. Flumenazil inhibits benzodiazepine-induced sedation, motor impairment, and ventilator depression.
Product Unit Size | Cost | Quantity | Stock |
---|
Flumazenil is an antagonist at GABA-A receptors that is used as a stimulant to counteract the effects of benzodiazepines. Flumenazil inhibits benzodiazepine-induced sedation, motor impairment, and ventilator depression.
Cas No. | 78755-81-4 |
---|---|
Purity | ≥98% |
Formula | C15H14FN3O3 |
Formula Wt. | 303.29 |
Chemical Name | 8-Fluoro-5,6-dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepinne-3-carboxylic acid ethyl ester |
IUPAC Name | ethyl 8-fluoro-5-methyl-6-oxo-4H-imidazo[1,5-a][1, 4]benzodiazepine-3-carboxylate |
Synonym | Anexate, Ro-15-1788, Lanexat, Romazicon |
Melting Point | 201-203°C |
Solubility | Soluble in water (128mg/L). |
Appearance | A white or almost white crystalline powder |
Store Temp | 4°C |
---|---|
Ship Temp | Ambient |
MSDS | |
---|---|
Info Sheet |
Rye DB, Bliwise DL, Parker K, et al. Modulation of vigilance in the primary hypersomnias by endogenous enhancement of GABAA receptors. Sci Transl Med. 2012 Nov 21;4(161):161ra151. PMID: 23175709.
Lader M. Benzodiazepines revisited--will we ever learn? Addiction. 2011 Dec;106(12):2086-109. PMID: 21714826.
NSAID; COX-1/2 inhibitor.
Benzisoxazole; 5-HT7 and NMDA agonist, D-amino ...
Cannabinoid receptor 2 selective agonist.
Dihydropyridine, FIASMA; L-type Ca2+ channel bl...
Optically active isomer of ibuprofen, NSAID; CO...
Triterpene saponin found in species of Panax; 2...
Selective cannabinoid receptor 2 (CB2) inverse ...
Isoflavone, phytoestrogen found in soy; ER agon...
Lck, Src, SIK inhibitor.
CB1 agonist, TRPV1 agonist.
Endogenous peptide hormone, involved in cell gr...
Fibrate; PPARα agonist.
FIASMA, 5-HT3 and σ1 agonist, SERT inhibitor.<...
Mycotoxin that has structural similarity to est...
Polyketide found in Setophoma.
Recombinant HIV-1 antigen fragment.
Endogenous neurotransmitter; GABA agonist.
Lactone found in fungi such as Eupenicillium; g...
SIRT1/2 inhibitor.
Glycosaminoglycan