Description
CEP-28122 is an ALK inhibitor. It inhibits tumor growth in ALK positive anaplastic large-cell lymphoma (ALCL), non-small cell lung cancer (NSCLC), and neuroglastoma cells.
Product Unit Size | Cost | Quantity | Stock |
---|
CEP-28122 is an ALK inhibitor. It inhibits tumor growth in ALK positive anaplastic large-cell lymphoma (ALCL), non-small cell lung cancer (NSCLC), and neuroglastoma cells.
Cas No. | 1022958-60-6 |
---|---|
Purity | ≥98% |
Formula | C28H35ClN6O3 |
Formula Wt. | 539.08 |
IUPAC Name | (1S,2S,3R,4R)-3-[(5-Chloro-2-{[(7S)-1-methoxy-7-(4-morpholinyl)-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl]amino}-4-pyrimidinyl)amino]bicyclo[2.2.1]hept-5-ene-2-carboxamide |
Synonym | CEP 28122, CEP28122 |
Store Temp | -20°C |
---|---|
Ship Temp | Ambient |
MSDS | |
---|---|
Info Sheet |
Cheng M., Quail M., et al. CEP-28122, a highly potent and selective orally active inhibitor of anaplastic lymphoma kinase with antitumor activity in experimental models of human cancers. Mol Cancer Ther. 11(3):670-79 (2012). PMID: 22203728.
May be useful against COVID-19
Basic phenol skeleton structure found in variou...
Endogenous tripeptide, involved in HPA signalin...
SERM, androgen modulator.
Calcium channel blocker.
Protease inhibitor.
Sulfonamide; folic acid synthesis inhibitor.
α1-adrenergic antagonist.
Read-through agent and nonsense mutation target...
Nucleoside (cytidine) analog; DNMT inhibitor, p...
NSAID; COX-2 inhibitor.
PAI-1 inhibitor.
Nucleotide analog; RT inhibitor.
Protein synthesis inhibitor, DPP2 and metallope...
Tretinoin analog; RARα/β/γ agonist.
Sulfonamide; PABA inhibitor.
Microtubule depolymerization inhibitor.
Triterpene saponin found in species of Panax; P...
GSK-3β, HGK, and CDK inhibitor.
Synthetic derivative of glycyrrhizin; connexin ...