Description
PP-121 an inhibitor of p110α PI3K, DNA-PK, mTORC1/2, Abl, Hck, Src, VEGFR2, and PDGFR that exhibits anticancer activity by inhibiting cellular proliferation.
| Product Unit Size | Cost | Quantity | Stock |
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PP-121 an inhibitor of p110α PI3K, DNA-PK, mTORC1/2, Abl, Hck, Src, VEGFR2, and PDGFR that exhibits anticancer activity by inhibiting cellular proliferation.
| Cas No. | 1092788-83-4 |
|---|---|
| Purity | ≥98% |
| Formula | C17H17N7 |
| Formula Wt. | 319.36 |
| IUPAC Name | 1-cyclopentyl-3-(1H-pyrrolo[2,3-b]pyridin-5-yl)pyrazolo[3,4-d]pyrimidin-4-amine |
| Solubility | DMSO 64 mg/mL (200.4 mM) Ethanol 2 mg/mL (6.26 mM) Water Insoluble |
| Appearance | White Crystal Powder |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
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| Info Sheet | |
| Brochures |
Apsel B, Blair JA, Gonzalez B, et al. Targeted polypharmacology: discovery of dual inhibitors of tyrosine and phosphoinositide kinases. Nat Chem Biol. 2008 Nov;4(11):691-9. PMID: 18849971.
RXR agonist.
p110β PI3K inhibitor.
Nitrosourea, DNA cross-linker.
ATP-sensitive K+ channel activator, α-adrenerg...
Oxidative phosphorylation inhibitor.
Smoothened agonist.
Sulforaphane-cysteine conjugate.
Synthesis impurity
Flavanone found in species of Citrus; L-type Ca...
Flavonol found in Tagetes.
Triterpene saponin found in species of Panax.
CysLT1 antagonist.
β-adrenergic antagonist, voltage-gated Na+ and...
Highly selective inhibitor
Flavonoid originally found in Silybum (milk thi...
Recombinant protein containing Treponema pallid...
Peptide, used to tag proteins for affinity chro...
HDAC inhibitor, mammalian RNA splicing modulato...
JAK2 inhibitor
Benzylisoquinoline alkaloid originally found in...