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β-Lipotropin (61-64) is a fragment of β-lipotropin that retains lipotropin’s morphinomimetic activity. β-Lipotropin (61-64) is also a fragment of met-enkephalin, one of several cleavage products of β-lipotropin. This fragment of β-lipotropin activates melanocytes to produce melanin and increase lipolysis and steroidogenesis. Additionally, this peptide inhibits smooth muscle contractions.
| Cas No. | 60254-82-2 |
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| Purity | ≥95% |
| Formula | C22H26N4O6 |
| Formula Wt. | 442.48 |
| IUPAC Name | 2-[[2-[[2-[[2-amino-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino]-3-phenylpropanoic acid |
| Store Temp | -20°C |
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| Ship Temp | Ambient |
| Info Sheet |
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Spiess J, Mount CD, Nicholson WE, et al. NH2-terminal amino acid sequence and peptide mapping of purified human beta-lipotropin: comparison with previously proposed sequences. Proc Natl Acad Sci U S A. 1982 Aug;79(16):5071-5. PMID: 6956916.
Ling N, Guillemin R. Morphinomimetic activity of synthetic fragments of beta-lipotropin and analogs. Proc Natl Acad Sci U S A. 1976 Sep;73(9):3308-10. PMID: 1067621.
Lazarus LH, Ling N, Guillemin R. beta-Lipotropin as a prohormone for the morphinomimetic peptides endorphins and enkephalins. Proc Natl Acad Sci U S A. 1976 Jun;73(6):2156-9. PMID: 1064883.