(−)-Epicatechin

Product ID E6231

Cas No. 490-46-0

Purity ≥93%

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Product Info
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Description
Product Info
Shipping and Storage
Downloads
References
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Description

(-)-Epicatechin (EC) is a flavanol and catechin originally found in Camilla and other plant sources; it exhibits antioxidative, neuroprotective, anti-atherosclerotic, and cardioprotective activities. In animal models of myocardial ischemia/reperfusion, EC decrease infarct size and improves mitochondrial respiration. In animal models of Alzheimer’s disease, EC decreases levels of amyloid-β (Aβ) in the brain and serum, suppressing neuroinflammation. EC also decreases atherosclerotic lesion area, lowering levels of SAA and CRP in vivo.

Product Info

Cas No.	490-46-0
Purity	≥93%
Formula	C₁₅H₁₄O₆
Formula Wt.	290.27
Chemical Name	2-(3,4-Dihydroxyphenyl)-3,4-dihydro-2H-1-benzo- pyran-3,5,7-triol
IUPAC Name	(2R,3R)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-2H-chromene-3,5,7-triol
Synonym	Epicatechin, Epicatechol
Melting Point	240°C (dec)
Solubility	Soluble in water or alcohol.
Appearance	White Crystal Powder

Shipping and Storage

Store Temp	-20°C
Ship Temp	Ambient

Downloads

MSDS	E6231 MSDS PDF
Info Sheet	E6231 Info Sheet PDF
Brochures	Green Tea Flyer
Brochures	Natural Products Flyer

References

Yamazaki KG, Andreyev AY, Ortiz-Vilchis P, et al. Intravenous (-)-epicatechin reduces myocardial ischemic injury by protecting mitochondrial function. Int J Cardiol. 2014 Aug 1;175(2):297-306. PMID: 24908200.

Zeng YQ, Wang YJ, Zhou XF. Effects of (-)Epicatechin on the Pathology of APP/PS1 Transgenic Mice. Front Neurol. 2014 May 9;5:69. PMID: 24847308.

Morrison M, van der Heijden R, Heeringa P, et al. Epicatechin attenuates atherosclerosis and exerts anti-inflammatory effects on diet-induced human-CRP and NFκB in vivo. Atherosclerosis. 2014 Mar;233(1):149-56. PMID: 24529136.

Butt MS, Ahmad RS, Sultan MT, et al. Green tea and anticancer perspectives: Updates from last decade. Crit Rev Food Sci Nutr. 2013 Sep 20. [Epub ahead of print]. PMID: 24915354.