LKT Labs

Biochemicals for Life Science Research

(−)-Epicatechin

Product ID E6231
Cas No. 490-46-0
Purity ≥93%
Product Unit SizeCostQuantityStock
1 mg $47.60 In stock
5 mg $122.60 In stock
25 mg $374.90 In stock
100 mg $885.70 In stock
Bulk Quote

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Description

(-)-Epicatechin (EC) is a flavanol and catechin originally found in Camilla and other plant sources; it exhibits antioxidative, neuroprotective, anti-atherosclerotic, and cardioprotective activities. In animal models of myocardial ischemia/reperfusion, EC decrease infarct size and improves mitochondrial respiration. In animal models of Alzheimer’s disease, EC decreases levels of amyloid-β (Aβ) in the brain and serum, suppressing neuroinflammation. EC also decreases atherosclerotic lesion area, lowering levels of SAA and CRP in vivo.

Product Info

Cas No.

490-46-0
Purity

≥93%
Formula

C15H14O6
Formula Wt.

290.27
Chemical Name

2-(3,4-Dihydroxyphenyl)-3,4-dihydro-2H-1-benzo- pyran-3,5,7-triol
IUPAC Name

(2R,3R)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-2H-chromene-3,5,7-triol
Synonym

Epicatechin, Epicatechol

Melting Point

240°C (dec)

Solubility

Soluble in water or alcohol.
Appearance

White Crystal Powder

Shipping and Storage

Store Temp

-20°C
Ship Temp

Ambient

Downloads

MSDS

E6231 MSDS PDF
Info Sheet

E6231 Info Sheet PDF
Brochures

Green Tea Flyer

Brochures

Natural Products Flyer

References

Yamazaki KG, Andreyev AY, Ortiz-Vilchis P, et al. Intravenous (-)-epicatechin reduces myocardial ischemic injury by protecting mitochondrial function. Int J Cardiol. 2014 Aug 1;175(2):297-306. PMID: 24908200.

Zeng YQ, Wang YJ, Zhou XF. Effects of (-)Epicatechin on the Pathology of APP/PS1 Transgenic Mice. Front Neurol. 2014 May 9;5:69. PMID: 24847308.

Morrison M, van der Heijden R, Heeringa P, et al. Epicatechin attenuates atherosclerosis and exerts anti-inflammatory effects on diet-induced human-CRP and NFκB in vivo. Atherosclerosis. 2014 Mar;233(1):149-56. PMID: 24529136.

Butt MS, Ahmad RS, Sultan MT, et al. Green tea and anticancer perspectives: Updates from last decade. Crit Rev Food Sci Nutr. 2013 Sep 20. [Epub ahead of print]. PMID: 24915354.

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