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10-Acetyl Docetaxel

Product ID D564088
Cas No. 125354-16-7
Purity ≥98%
Product Unit SizeCostQuantityStock
1 mg $150.00 In stock
5 mg $388.50 In stock
10 mg $715.50 In stock
25 mg $1,499.10 In stock
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  • Description
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Description

10-Acetyl Docetaxel is an analog of the anti-cancer agent, docetaxel. This analog appears not to have activity in the microtubule assembly assay.

Product Info

Cas No.

125354-16-7

Purity

≥98%

Formula

C45H55NO15

Formula Wt.

849.92

Chemical Name

[(1S,2S,3R,4S,7R,9S,10S,12R,15S)-4,12-diacetyloxy-1,9-dihydroxy-15-[(2R,3S)-2-hydroxy-3-[(2-methylpropan-2-yl)oxycarbonylamino]-3-phenylpropanoyl]oxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.03,10.04,7]heptadec-13-en-2-yl] benzoate

IUPAC Name

[(1S,2S,3R,4S,7R,9S,10S,12R,15S)-4,12-diacetyloxy-1,9-dihydroxy-15-[(2R,3S)-2-hydroxy-3-[(2-methylpropan-2-yl)oxycarbonylamino]-3-phenylpropanoyl]oxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.03,10.04,7]heptadec-13-en-2-yl] benzoate

Synonym

Docetaxal, Docetaxel EP Impurity G, 5β,20-Epoxy-1,7β-dihydroxy-9-oxotax-11-ene-2α,4,10β,13α-tetrayl 4,10-diacetate 2-benzoate 13-[(2R,3S)-3-[[(1,1-dimethylethoxy)carbonyl]amino]-2-hydroxy-3-henylpropanoate] , 

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

D564088 MSDS PDF

Info Sheet

D564088 Info Sheet PDF

References

Datta A1, Jayasinghe LR, Georg GI. 4-Deacetyltaxol and 10-acetyl-4-deacetyltaxotere: synthesis and biological evaluation. J Med Chem. 1994 Nov 25;37(24):4258-60. PMID: 7990125

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