Description
10-Acetyl Docetaxel is an analog of the anti-cancer agent, docetaxel. This analog appears not to have activity in the microtubule assembly assay.
Product Unit Size | Cost | Quantity | Stock |
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10-Acetyl Docetaxel is an analog of the anti-cancer agent, docetaxel. This analog appears not to have activity in the microtubule assembly assay.
Cas No. | 125354-16-7 |
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Purity | ≥98% |
Formula | C45H55NO15 |
Formula Wt. | 849.92 |
Chemical Name | [(1S,2S,3R,4S,7R,9S,10S,12R,15S)-4,12-diacetyloxy-1,9-dihydroxy-15-[(2R,3S)-2-hydroxy-3-[(2-methylpropan-2-yl)oxycarbonylamino]-3-phenylpropanoyl]oxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.03,10.04,7]heptadec-13-en-2-yl] benzoate |
IUPAC Name | [(1S,2S,3R,4S,7R,9S,10S,12R,15S)-4,12-diacetyloxy-1,9-dihydroxy-15-[(2R,3S)-2-hydroxy-3-[(2-methylpropan-2-yl)oxycarbonylamino]-3-phenylpropanoyl]oxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.03,10.04,7]heptadec-13-en-2-yl] benzoate |
Synonym | Docetaxal, Docetaxel EP Impurity G, 5β,20-Epoxy-1,7β-dihydroxy-9-oxotax-11-ene-2α,4,10β,13α-tetrayl 4,10-diacetate 2-benzoate 13-[(2R,3S)-3-[[(1,1-dimethylethoxy)carbonyl]amino]-2-hydroxy-3-henylpropanoate] , |
Store Temp | -20°C |
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Ship Temp | Ambient |
MSDS | |
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Info Sheet |
Datta A1, Jayasinghe LR, Georg GI. 4-Deacetyltaxol and 10-acetyl-4-deacetyltaxotere: synthesis and biological evaluation. J Med Chem. 1994 Nov 25;37(24):4258-60. PMID: 7990125
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