• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
7-Methyl-6-mercaptopurine

7-Methyl-6-mercaptopurine

Product ID M1575
Cas No. 3324-79-6
Purity ≥87%
Product Unit SizeCostQuantityStock
10 mg $92.00 In stock
50 mg $204.30 In stock
100 mg $330.50 In stock
500 mg $901.30 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

7-Methyl-6-mercaptopurine is a thiopurine antimetabolite and derivative of 6-mercaptopurine; it exhibits immunosuppressive, anti-inflammatory, and anticancer chemotherapeutic activities. This compound is clinically used to treat inflammatory bowel disorder (IBD), Crohn’s disease, and leukemias and lymphomas. This compound suppresses metabolism of inosine monophosphate (IMP), inhibiting phosphoribosylpyrophosphate amidotransferase; this prevents synthesis of purines, DNA, and RNA.

Product Info

Cas No.

3324-79-6

Purity

≥87%

Formula

C6H6N4S

Formula Wt.

166.21

Chemical Name

1,7-dihydro-7-methyl-6H-Purine-6-thione

IUPAC Name

7-methyl-3H-purine-6-thione

Synonym

7-Methyl-6-thiopurine, 7-Methylpurine-6-thiol

Melting Point

286-288°C

Solubility

Soluble in DMSO.

Appearance

White Crystalline Powder

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

M1575 MSDS PDF

Info Sheet

M1575 Info Sheet PDF

References

Bradford K, Shih DQ. Optimizing 6-mercaptopurine and azathioprine therapy in the management of inflammatory bowel disease. World J Gastroenterol. 2011 Oct 7;17(37):4166-73. PMID: 22072847.

Nielsen OH, Vainer B, Rask-Madsen J. Review article: the treatment of inflammatory bowel disease with 6-mercaptopurine or azathioprine. Aliment Pharmacol Ther. 2001 Nov;15(11):1699-708. PMID: 11683683.

Lennard L, Welch JC, Lilleyman JS. Thiopurine drugs in the treatment of childhood leukaemia: the influence of inherited thiopurine methyltransferase activity on drug metabolism and cytotoxicity. Br J Clin Pharmacol. 1997 Nov;44(5):455-61. PMID: 9384462.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • B1992

    Bexarotene

    RXR agonist.

    ≥98%
  • A761003

    AT-7519 Hydrochloride

    ATP competitive CDK inhibitor.

    ≥98%
  • F5745

    Folic Acid

    Non-endogenous essential vitamin (B9), found in...

    ≥96%
  • L0284

    Lavendustin A

    Tyrosine kinase inhibitor.

    ≥97%
  • P6854

    Progesterone

    Endogenous steroid hormone involved in reproduc...

    ≥98%
  • N5409

    Nocodazole

    Microtubule polymerization inhibitor.

    ≥98%
  • P0255

    Pantoprazole

    H+/K+ ATPase and ROCK-2 inhibitor.

    ≥98%
  • A5301

    Anacetrapib

    Cholesterol ester transfer protein inhibitor.

    ≥98%
  • A5217

    trans-Anethole

    Phenylpropene derivative found in essential oil...

    ≥98%
  • V9228

    VX-765

    NLRP3 and caspase-1 inhibitor.

    ≥98%
  • L1981

    Leucokinin VIII

    Peptide found in insects.

    ≥95%
  • P0268

    Parasin I

    Histone H2-derived antimicrobial peptide found ...

    ≥95%
  • F5871

    N-formyl-Met-Leu-Phe-Lys

    Peptide, involved in neutrophil activation; FPR...

    ≥95%
  • V1854

    Venlafaxine Hydrochloride

    SERT, NET, MAO inhibitor.

    ≥98%
  • P8270

    Purvalanol A

    Purine derivative; CDK inhibitor.

    ≥98%
  • P698574

    Prolylrapamycin

    Rapamycin analog

  • A4523

    Alfuzosin Hydrochloride

    α1-adrenergic antagonist.

    ≥97%
  • C6956

    Crotamiton

    Antipruritic.

    ≥98%
  • D336486

    Dimethylamino Parthenolide

    Water-soluble parthenolide analog; NF-κB inhib...

    ≥98%
  • C0800

    C59

    PORCN inhibitor.

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only