Description
Acarbose is an anti-diabetic α-glucosidase inhibitor that decreases digestion of complex carbohydrates and prevents glucose absorption. Acarbose improves insulin sensitivity and decreases postprandial hyperglycemia.
Acarbose
Product ID A0802
Cas No. 56180-94-0
Purity ≥98%
| Product Unit Size | Cost | Quantity | Stock |
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Product Info
| Cas No. | 56180-94-0 |
|---|---|
| Purity | ≥98% |
| Formula | C25H43NO18 |
| Formula Wt. | 645.6 |
| Chemical Name | O-4,6-Dideoxy-4-[[[1S-(1α,4α,5-β,6α))-4,5,6- trihydroxy-3-(hydroxymethyl)-2-cyclohexen-1- yl]amino]-α-D-glucopyranosyl-(1-4)-O-α-D- glucopyranosyl-(1-4)-D-glucose |
| IUPAC Name | (3R,4R,5S,6R)-5-[(2R,3R,4R,5S,6R)-5-[(2R,3R,4S,5S,6R)-3, 4-dihydroxy-6-methyl-5-[[(1S,4R,5S,6S)-4,5, 6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino]oxan-2-yl]oxy-3, 4-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-6-(hydroxymethyl)oxane-2,3, 4-triol |
| Synonym | Bay g 5421, Glucobay, Prandase, Precose |
| Melting Point | 90°C |
| Solubility | Soluble in water (129mg/mL), methanol, ethanol (8mg/mL), and DMSO (129mg/mL) |
| Appearance | White to off white powder |
Shipping and Storage
| Store Temp | Ambient |
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| Ship Temp | Ambient |
Downloads
| MSDS | |
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| Info Sheet |
References
Jiang Z, He Q, Wezeman J, et al. A cocktail of rapamycin, acarbose, and phenylbutyrate prevents age-related cognitive decline in mice by targeting multiple pathways. Geroscience. 2024 Oct;46(5):4855-4868. PMID: 38755466.
Kalra S. Alpha glucosidase inhibitors. J Pak Med Assoc. 2014 Apr;64(4):474-6. PMID: 24864650.
Okada K, Yanagawa T, Warabi E, et al. The alpha-glucosidase inhibitor acarbose prevents obesity and simple steatosis in sequestosome 1/A170/p62 deficient mice. Hepatol Res. 2009 May;39(5):490-500. PMID: 19207582.
Hoffmann J, Spengler M. Efficacy of 24-week monotherapy with acarbose, metformin, or placebo in dietary-treated NIDDM patients: the Essen-II Study. Am J Med. 1997 Dec;103(6):483-90. PMID: 9428831.