• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Amifostine Trihydrate

Amifostine Trihydrate

Product ID A4933
Cas No. 112901-68-5
Purity ≥98%
Product Unit SizeCostQuantityStock
50 mg $85.20 In stock
100 mg $151.30 In stock
500 mg $529.30 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Amifostine is a thiol prodrug that exhibits antioxidative activity. Amifostine is co-administered with chemotherapeutics to detoxify their metabolites and scavenge for free radicals, protecting normal tissue and DNA against chemotherapy- or radiation-induced damage.

Product Info

Cas No.

112901-68-5

Purity

≥98%

Formula

C5H15N2O3PS • 3H2O

Formula Wt.

268.27

Chemical Name

Ethanethiol, 2-((3-aminopropyl)amino)-, dihydrogen phosphate (ester), trihydrate

IUPAC Name

2-(3-aminopropylamino)ethylsulfanylphosphonic acid

Synonym

Ethiofos, Gammaphos, SAPEP, Ethyol

Melting Point

160–161°C

Solubility

Soluble in water.

Appearance

White or almost white crystalline powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

A4933 MSDS PDF

Info Sheet

A4933 Info Sheet PDF

References

Chen C, Tian L, Zhang M, et al. Protective effect of amifostine on high-dose methotrexate-induced small intestinal mucositis in mice. Dig Dis Sci. 2013 Nov;58(11):3134-43. PMID: 23979434.

Lv W, Zhang M, Zhang Z, et al. Amifostine acts upon mitochondria to stimulate growth of bone marrow and regulate cytokines. Adv Exp Med Biol. 2013;789:195-201. PMID: 23852495.

Wozniak K, Gloc E, Morawiec Z, et al. Amifostine can differentially modulate DNA double-strand breaks and apoptosis induced by idarubicin in normal and cancer cells. Exp Oncol. 2008 Mar;30(1):22-8. PMID: 18438337.

Kouvaris JR, Kouloulias VE, Vlahos LJ. Amifostine: the first selective-target and broad-spectrum radioprotector. Oncologist. 2007 Jun;12(6):738-47. PMID: 17602063.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • M2409

    MGCD-0103

    HDAC inhibitor.

    ≥98%
  • D564090

    7-epi-Docetaxel

    Docetaxel impurity

    ≥95%
  • R327201

    Rifapentine

    Antibiotic

    ≥97%
  • P6865

    Propranolol Hydrochloride

    β1/2-adrenergic antagonist.

    ≥98%
  • E6896

    Erysolin

    ITC found in cruciferous vegetables, analog of ...

    ≥97%
  • M1565

    S-Methyl-L-cysteine-S-oxide

    Organosulfur found in cruciferous vegetables; a...

    ≥95%
  • A0961

    Adrenocorticotropic Hormone (1-39), rat

    Endogenous peptide hormone, involved in stress ...

    ≥95%
  • C9881

    Cytochalasin D

    Mycotoxin produced by Aspergillus; actin polyme...

    ≥98%
  • A046189

    Abexinostat

    Primarily targets HDAC1

    ≥98%
  • J766160

    JTE907

    Selective Cannabinoid receptor 2(CB2) inverse a...

    ≥98%
  • P2858

    4-α-Phorbol-12-myristate-13-acetate

    Negative control for PKC activation.

    ≥98%
  • P0369

    Parecoxib Sodium

    NSAID; COX-2 inhibitor.

    ≥99%
  • V3252

    Vinorelbine Ditartrate

    Semi-synthetic vinca alkaloid from Catharanthus...

    ≥98%
  • J0240

    JAK2 Inhibitor V

    JAK2 inhibitor.

    ≥98%
  • C0274

    Caspofungin Diacetate

    Lipopeptide; 1,3-β-Glucan synthase inhibitor.<...

    ≥95%
  • P5745

    Polygalic Acid

    Saponin found in Polygala.

    ≥97%
  • A7476

    Astaxanthin

    Carotenoid found in shrimp, salmon, and algae.<...

    ≥97%
  • I7459

    1-Isothiocyanato-8-(methylsulfinyl)-octane

    ITC found in Nasturtium officinale (watercress)...

    ≥98%
  • D1643

    Delta Sleep Inducing Peptide

    Peptide; GABA potentiator, NMDA negative allost...

    ≥95%
  • S3476

    Sitagliptin Phosphate Monohydrate

    DPP4 inhibitor.

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only