• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Amifostine Trihydrate

Amifostine Trihydrate

Product ID A4933
Cas No. 112901-68-5
Purity ≥98%
Product Unit SizeCostQuantityStock
50 mg $85.20 In stock
100 mg $151.30 In stock
500 mg $529.30 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Amifostine is a thiol prodrug that exhibits antioxidative activity. Amifostine is co-administered with chemotherapeutics to detoxify their metabolites and scavenge for free radicals, protecting normal tissue and DNA against chemotherapy- or radiation-induced damage.

Product Info

Cas No.

112901-68-5

Purity

≥98%

Formula

C5H15N2O3PS • 3H2O

Formula Wt.

268.27

Chemical Name

Ethanethiol, 2-((3-aminopropyl)amino)-, dihydrogen phosphate (ester), trihydrate

IUPAC Name

2-(3-aminopropylamino)ethylsulfanylphosphonic acid

Synonym

Ethiofos, Gammaphos, SAPEP, Ethyol

Melting Point

160–161°C

Solubility

Soluble in water.

Appearance

White or almost white crystalline powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

A4933 MSDS PDF

Info Sheet

A4933 Info Sheet PDF

References

Chen C, Tian L, Zhang M, et al. Protective effect of amifostine on high-dose methotrexate-induced small intestinal mucositis in mice. Dig Dis Sci. 2013 Nov;58(11):3134-43. PMID: 23979434.

Lv W, Zhang M, Zhang Z, et al. Amifostine acts upon mitochondria to stimulate growth of bone marrow and regulate cytokines. Adv Exp Med Biol. 2013;789:195-201. PMID: 23852495.

Wozniak K, Gloc E, Morawiec Z, et al. Amifostine can differentially modulate DNA double-strand breaks and apoptosis induced by idarubicin in normal and cancer cells. Exp Oncol. 2008 Mar;30(1):22-8. PMID: 18438337.

Kouvaris JR, Kouloulias VE, Vlahos LJ. Amifostine: the first selective-target and broad-spectrum radioprotector. Oncologist. 2007 Jun;12(6):738-47. PMID: 17602063.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • P1852

    Penicillin G procaine

    Hydrophobic β-lactam; penicillin binding prote...

    ≥98%
  • S543721

    SNS-032

    Inhibitor of CDK.

    ≥99%
  • L0528

    LBH-589

    HDAC1/2/3/11 inhibitor.

    ≥98%
  • J5237

    JNJ-26854165

    MDM2 inhibitor.

    ≥98%
  • H5748

    D,L-Homocysteine Thiolactone Hydrochloride

    Heterocyclic derivative of cysteine, alters pro...

    ≥99%
  • S1061

    Small Cardioactive Peptide B

    Peptide found in molluscs, cardiomodulator.

    ≥95%
  • S8243

    Sulbactam Sodium

    β-lactamase inhibitor.

    ≥98%
  • M3344

    Milrinone

    PDE3 inhibitor.

    ≥98%
  • C577524

    Concanamycin A

    Macrolide lactone antibiotic.

    ≥98%
  • P2303

    Phallacidin

    Phallotoxin found in Amanita phalloides; microt...

    ≥98%
  • Q8135

    Quinestrol

    Synthetic steroid hormone, estrogen analog, use...

    ≥98%
  • F4420

    Boc-FLFLF

    Peptide; FRP1 antagonist.

    ≥95%
  • G3456

    Ginsenoside Rd

    Triterpene saponin found in species of Panax; 2...

    ≥98%
  • P2502

    Phenethyl Glucosinolate Potassium

    Found in cruciferous vegetables.

    ≥97%
  • C0025

    Cafestol Eicosanate

    Diterpene found in brewed, unfiltered coffee; F...

    ≥98%
  • F4679

    Flubendazole

    Benzimidazole; microtubule polymerization inhib...

    ≥98%
  • A0970

    Adrenocorticotropic Hormone (18-39), human

    Endogenous peptide hormone fragment, involved i...

    ≥95%
  • P7033

    Primaquine Phosphate

    Alters membrane permeability, prevents transpor...

    ≥98% (titration)
  • E5217

    β-Endorphin, human

    Endogenous opioid peptide; μOR agonist.

    ≥95%
  • P1845

    Pelitinib

    EGFR inhibitor.

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only