LKT Labs

Biochemicals for Life Science Research

Awaiting product image

Amylin, human

Product ID A4847
Cas No. 122384-88-7
Purity ≥95%
Product Unit SizeCostQuantityStock
0.5 mg $279.00 Please Inquire
1 mg $545.00 In stock
2.5 mg $790.00 In stock
Bulk Quote

Quicklinks

Description

Amylin is also known as islet amyloid precursor peptide (IAPP) and is co-secreted with insulin from pancreatic β-cells. Amylin is an endogenous peptide hormone that exhibits gastrointestinal motility modulating activity, decreasing gastric emptying and suppressing gastric acid secretion; these actions slow food intake, preventing blood glucose spikes after eating and decreasing insulin demand. Misguided IAPP processing plays a significant role in the development of diabetes mellitus type 2. Like calcitonin, IAPP inhibits osteoclast activity and Ca2+ reabsorption in bones. This peptide binds to calcitonin-RAMP complexes.

Product Info

Cas No.

122384-88-7
Purity

≥95%
Formula

C165H261N51O55S2
Formula Wt.

3903.4
Synonym

Amlintide
Solubility

Soluble in 5% acetic acid.

Appearance

White to off white powder

Shipping and Storage

Store Temp

-20°C
Ship Temp

Ambient

Downloads

MSDS

A4847 MSDS PDF
Info Sheet

A4847 Info Sheet PDF

References

Paulsson JF, Westermark GT. Aberrant processing of human proislet amyloid polypeptide results in increased amyloid formation. Diabetes. 2005 Jul;54(7):2117-25. PMID: 15983213.

Ratner RE, Dickey R, Fineman M, et al. Amylin replacement with pramlintide as an adjunct to insulin therapy improves long-term glycaemic and weight control in Type 1 diabetes mellitus: a 1-year, randomized controlled trial. Diabet Med. 2004 Nov;21(11):1204-12. PMID: 15498087.

Pittner RA, Albrandt K, Beaumont K, et al. Molecular physiology of amylin. J Cell Biochem. 1994;55 Suppl:19-28. PMID: 7929615.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • R1626

    Regorafenib Monohydrate

    VEGFR1/2/3, TIE2, PDGFRβ, FGFR1, c-Kit, RET, B...

    ≥99%
  • O2146

    R-(+)-Ofloxacin

    Fluoroquinolone, optically active isomer of ofl...

    ≥98%
  • T7158

    Tropicamide

    mAChR antaonist.

    ≥98%
  • F5869

    N-formyl-Met-Ala-Ser

    Peptide, involved in neutrophil activation; FPR...

    ≥95%
  • E4444

    Ellagic Acid

    Phenol found in various fruits; HDAC modulator....

    ≥98%
  • E0929

    Echinacoside

    Phenylethanoid glycoside found in Echinacea.

    ≥98%
  • S8110

    Sucralfate

    Antacid; pepsin inhibitor. Assay (Polysaccharid...

    Assay (Polysaccharide sulfate) 30-38%
  • J8800

    JW55

    TNKS1/2 inhibitor.

    ≥98%
  • A064766

    ABT 639

    T-type calcium channel blocker

    ≥99%
  • P7628

    Parathyroid Hormone-Related Protein (1-34), human/rat

    Endogenous peptide hormone, increases extracell...

    ≥95%
  • P6800

    Pravastatin Lactone

    Statin; HMG-CoA reductase inhibitor.

    ≥98%
  • S0224

    SAG

    Smoothened agonist.

    ≥98%
  • B0108

    Bactenecin

    Cathelicidin derivative, antimicrobial peptide,...

    ≥95%
  • C6800

    (R)-CR8

    Roscovitine analog; CDK inhibitor.

    ≥98%
  • A4445

    Allopurinol

    Purine (hypoxanthine) analog; xanthine oxidase ...

    ≥98%
  • M1622

    Mefenamic Acid

    NSAID; GABA-A potentiator, COX-1/2 inhibitor.

    ≥98%
  • G3460

    Ginsenoside F1

    Triterpene saponin found in species of Panax.

    ≥98%
  • P6852

    Propafenone Hydrochloride

    β-adrenergic antagonist, Kv1.4 and K2P2 K+ cha...

    ≥98%
  • Z3463

    Ziprasidone

    5-HT1A agonist, D2, 5-HT1D antagonist.

    ≥98%
  • A5033

    4-Aminosalicylic Acid

    Dihydrofolate reductase inhibitor.

    ≥98%