Description
AT-121 is a bifunctional agonist of the nociceptin/orphanin FQ peptide and mu opioid peptide receptors.
| Product Unit Size | Cost | Quantity | Stock |
|---|
AT-121 is a bifunctional agonist of the nociceptin/orphanin FQ peptide and mu opioid peptide receptors.
| Cas No. | 2099681-31-7 |
|---|---|
| Purity | ≥98% |
| Formula | C24H38N4O3S |
| Formula Wt. | 462.65 |
| Chemical Name | N-[2-[1,2-dihydro-1'-[cis-4-(1-methylethyl)cyclohexyl]-3-oxospiro[isoquinoline-4(3H),4'-piperidin]-2-yl]ethyl]-sulfamide 3-oxo-1'-(4-propan-2-ylcyclohexyl)-2-[2-(sulfamoylamino)ethyl]spiro[1H-isoquinoline-4,4'-piperidine] |
| IUPAC Name | 3-oxo-1'-(4-propan-2-ylcyclohexyl)-2-[2-(sulfamoylamino)ethyl]spiro[1H-isoquinoline-4,4'-piperidine] |
| Synonym | AT121 |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| Info Sheet |
|---|
Ding H, Kiguchi N, Yasuda D, et al. A bifunctional nociceptin and mu opioid receptor agonist is analgesic without opioid side effects in nonhuman primates. Sci Transl Med. 2018 Aug 29;10(456):eaar3483. PMID: 30158150.
AChE and BChE inhibitor.
Androgen receptor downregulator.
Found in hawthorn.
InsR and IGF-1R inhibitor.
Coenzyme, vitamin found in dairy, meat, eggs, f...
Isoquinoline alkaloid found in various plant so...
Polyketide; CRM1 inhibitor.
ATP-sensitive K+ channel activator, α-adrenerg...
Protease inhibitor.
β-lactamase inhibitor.
Valsartan impurity
Hydrophobic β-lactam; penicillin binding prote...
DNA alkylator.
Phenylamino pyridine; Abl, c-Kit, PDGFR, PP2A i...
ROCK1/2 inhibitor, potential RSK and p70S6K inh...
Antimicrobial peptide found in Apis mellifera.<...
Cysteine-ITC conjugate, antioxidant.
Polyphenol found in Gossypium; calcineurin and ...
Isoquinoline alkaloid found in Corydalis, Phell...
Organosulfur found in garlic; Microtubule polym...