Description
AT-121 is a bifunctional agonist of the nociceptin/orphanin FQ peptide and mu opioid peptide receptors.
| Product Unit Size | Cost | Quantity | Stock |
|---|
AT-121 is a bifunctional agonist of the nociceptin/orphanin FQ peptide and mu opioid peptide receptors.
| Cas No. | 2099681-31-7 |
|---|---|
| Purity | ≥98% |
| Formula | C24H38N4O3S |
| Formula Wt. | 462.65 |
| Chemical Name | N-[2-[1,2-dihydro-1'-[cis-4-(1-methylethyl)cyclohexyl]-3-oxospiro[isoquinoline-4(3H),4'-piperidin]-2-yl]ethyl]-sulfamide 3-oxo-1'-(4-propan-2-ylcyclohexyl)-2-[2-(sulfamoylamino)ethyl]spiro[1H-isoquinoline-4,4'-piperidine] |
| IUPAC Name | 3-oxo-1'-(4-propan-2-ylcyclohexyl)-2-[2-(sulfamoylamino)ethyl]spiro[1H-isoquinoline-4,4'-piperidine] |
| Synonym | AT121 |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| Info Sheet |
|---|
Ding H, Kiguchi N, Yasuda D, et al. A bifunctional nociceptin and mu opioid receptor agonist is analgesic without opioid side effects in nonhuman primates. Sci Transl Med. 2018 Aug 29;10(456):eaar3483. PMID: 30158150.
Synthetic steroid used in HRT; PR, AR, glucocor...
HIV integrase inhibitor.
ALK4/5/7 (activin-like) inhibitor, TGF-β inhib...
Pentacyclic triterpene found in various plant s...
Endogenous sphingolipid involved in cell signal...
FIASMA, μOR agonist, potential HCN channel blo...
c-Raf, RET, VEGFR1 inhibitor, potential HMT inh...
Melatonin analog; MT1/2 agonist.
Inhibitor of ALK2, ALK3, ALK6, and AMPK.
Indoline; PDGFR, VEGFR, c-KIT, FLT3, mTORC1 inh...
Polyphenol found in Camilla sinensis; HIV integ...
pan-RAF inhibitor
Insecticide; α-adrenergic agonist, MAO inhibit...
Phthalide; PPARγ agonist, IMPDH inhibitor, mic...
Protein synthesis inhibitor, DPP2 and metallope...
GSK3 and AChE inhibitor, potential σ1 agonist....
NMDA NR1/NR2B antagonist.
Synthetic non-steroid endocrine disrupter; ER a...
ALK inhibitor.
Indoline; D2/3 agonist.