Description
AT-121 is a bifunctional agonist of the nociceptin/orphanin FQ peptide and mu opioid peptide receptors.
| Product Unit Size | Cost | Quantity | Stock |
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AT-121 is a bifunctional agonist of the nociceptin/orphanin FQ peptide and mu opioid peptide receptors.
| Cas No. | 2099681-31-7 |
|---|---|
| Purity | ≥98% |
| Formula | C24H38N4O3S |
| Formula Wt. | 462.65 |
| Chemical Name | N-[2-[1,2-dihydro-1'-[cis-4-(1-methylethyl)cyclohexyl]-3-oxospiro[isoquinoline-4(3H),4'-piperidin]-2-yl]ethyl]-sulfamide 3-oxo-1'-(4-propan-2-ylcyclohexyl)-2-[2-(sulfamoylamino)ethyl]spiro[1H-isoquinoline-4,4'-piperidine] |
| IUPAC Name | 3-oxo-1'-(4-propan-2-ylcyclohexyl)-2-[2-(sulfamoylamino)ethyl]spiro[1H-isoquinoline-4,4'-piperidine] |
| Synonym | AT121 |
| Store Temp | -20°C |
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| Ship Temp | Ambient |
| Info Sheet |
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Ding H, Kiguchi N, Yasuda D, et al. A bifunctional nociceptin and mu opioid receptor agonist is analgesic without opioid side effects in nonhuman primates. Sci Transl Med. 2018 Aug 29;10(456):eaar3483. PMID: 30158150.
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Non-opioid analgesic.
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AurKA/B inhibitor.
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