Azithromycin Dihydrate

Name: Azithromycin Dihydrate
SKU: A9834
Availability: InStock

Product ID A9834

Cas No. 117772-70-0

Purity ≥98%

Product Unit Size	Cost	Quantity		Stock

Bulk Quote

Quicklinks

Description
Product Info
Shipping and Storage
Downloads
References

Description

Azithromycin is an azalide macrolide antibiotic derived from erythromycin. Azithromycin binds the bacterial 50S ribosomal subunit, inhibiting protein translation. Azithromycin displays antibacterial, anti-fibrotic, and anti-inflammatory activities. In epithelial cells, azithromycin inhibits the epithelial-to-mesenchymal transition (EMT) by inhibiting expression of Smad3. Additionally, azithromycin inhibits production of arachidonic acid, eicosanoids, IL-6, and IL-12 in LPS-stimulated macrophages.

Product Info

Cas No.	117772-70-0
Purity	≥98%
Formula	C₃₈H₇₂N₂O₁₂ • 2H₂O
Formula Wt.	785.02
Chemical Name	[2R-(2R,3S,4R,5R,8R,10R,11R,12S,13S,- 14R)]-13-[(2,6-Dideoxy-3-C-methyl-3-O-methyl-α- L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-[[3,4,6-trideoxy-3- (dimethylamio)-β-D-xylo-hexopyranosyl]oxy]-1-oxa- 6-azacyclopentadecan-15-one
IUPAC Name	(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-11-[(2S,3R,4S, 6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-2-ethyl-3,4, 10-trihydroxy-13-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4, 6-dimethyloxan-2-yl]oxy-3,5,6,8,10,12, 14-heptamethyl-1-oxa-6-azacyclopentadecan-15-one
Synonym	Azitrocin, Ribotrex, Sumamed, Zithromax, Zitromax
Melting Point	113-115°C
Solubility	Slightly soluble in water. DMSO:100 mg/mL, Ethanol:100 mg/mL.
Appearance	White Crystal Powder

Shipping and Storage

Store Temp	Ambient
Ship Temp	Ambient

Downloads

MSDS	A9834 MSDS PDF
Info Sheet	A9834 Info Sheet PDF

References

Bakheit AH, Al-Hadiya BM, Abd-Elgalil AA. Azithromycin. Profiles Drug Subst Excip Relat Methodol. 2014;39:1-40. PMID: 24794904.

Medina CA, Rowe AM, Yun H, et al. Azithromycin treatment increases survival of high-risk corneal allotransplants. Cornea. 2013 May;32(5):658-66. PMID: 23407315.

Banerjee B, Musk M, Sutanto EN, et al. Regional differences in susceptibiity of bronchial epithelium to mesenchymal transition and inhibition by the macrolide antibiotic azithromycin. PLoS One. 2012;7(12):e52309. PMID: 23284981.

Banjanac M, Munić Kos V, Nujić K, et al. Anti-inflammatory mechanism of action of azithromycin in LPS-stimulated J774A.1 cells. Pharmacol Res. 2012 Oct;66(4):357-62. PMID: 22766077.

Togami K, Chono S, Morimoto K. Distribution characteristics of clarithromycin and azithromycin, macrolide antimicrobial agents used for treatment of respiratory infections, in lung epithelial lining fluid and alveolar macrophages. Biopharm Drug Dispos. 2011 Oct;32(7):389-397. PMID: 21812004.

Custom Order

Name*
First Last
Company/Institution
Email*
Enter Email Confirm Email
Product ID
Product Name
Unit Size
Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
Unit Label
Quantity
Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
Comments
Name
This field is for validation purposes and should be left unchanged.

Azithromycin Dihydrate

Quicklinks

Description

Product Info

Shipping and Storage

Downloads

References

Custom Order

Related Products

RF-NH2

Neuropeptide Y (3-36), human

Raltegravir

β-Endorphin, camel

Clofarabine

Cantharidin

GDC-6036

Fluticasone Propionate

Salmon Calcitonin Acetate

Disodium Cycloheptylaminomethylene Diphosphate

Concanamycin A

Fibronectin CS-1 Peptide

Bradykinin (1-3)

NVP-LDE225 Diphosphate

Thiostrepton

Atriopeptin II, rat/rabbit/mouse

Risedronate Sodium Hydrate

Puupehenone

Harringtonine

19-O-Demethyl rapamycin

Footer