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Balicatib

Balicatib

Product ID B0245
Cas No. 354813-19-7
Purity ≥98%
Product Unit SizeCostQuantityStock
5 mg $143.70 In stock
25 mg $472.50 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Balicatib is an inhibitor of cathepsin K that displays anti-resorptive activity. Balicatib inhibits osteoclast activity, decreasing bone turnover and increasing bone mineral density and bone formation rates.

Product Info

Cas No.

354813-19-7

Purity

≥98%

Formula

C23H33N5O2

Formula Wt.

411.55

IUPAC Name

N-{1-[(Cyanomethyl)carbamoyl]cyclohexyl}-4-(4-propyl-1-piperazinyl)benzamide

Synonym

AAE-581

Solubility

DMSO: ≥ 46 mg/mL

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

B0245 MSDS PDF

Info Sheet

B0245 Info Sheet PDF

References

Jerome C, Missbach M, Gamse R. Balicatib, a cathepsin K inhibitor, stimulates periosteal bone formation in monkeys. Osteoporos Int. 2012 Jan;23(1):339-49. PMID: 21380636.

Chappard D, Libouban H, Mindeholm L, et al. The cathepsin K inhibitor AAE581 induces morphological changes in osteoclasts of treated patients. Microsc Res Tech. 2010 Jul;73(7):726-32. PMID: 20025055.

Custom Order

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