Description
BAY-1251152 is an inhibitor of PTEFb/CDK9. PTEFb contributes to the regulation of gene transcription and can be over-expressed in cancer cells, leading to the transcription of key tumor-promoting genes and proliferation.
BAY-1251152
Product ID B030962
Cas No. 1610358-56-9
Purity ≥98%
| Product Unit Size | Cost | Quantity | Stock |
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Product Info
| Cas No. | 1610358-56-9 |
|---|---|
| Purity | ≥98% |
| Formula | C19H18F2N4O2S |
| Formula Wt. | 404.44 |
| IUPAC Name | 5-Fluoro-4-(4-fluoro-2-methoxyphenyl)-N-{4-[(S-methylsulfonimidoyl)methyl]-2-pyridinyl}-2-pyridinamine |
| Synonym | BAY 1251152, BAY1251152 |
Shipping and Storage
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
Downloads
| MSDS | |
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| Info Sheet |
References
Luecking U., Scholz A., et al. Identification of potent and highly selective PTEFb inhibitor BAY 1251152 for the treatment of cancer: from p.o. to i.v. application via scaffold hops. Cancer Res. 77(13 Suppl):Abstract nr 984 (2017).