Description
C-176 is a covalent inhibitor of STING.
| Product Unit Size | Cost | Quantity | Stock |
|---|
C-176 is a covalent inhibitor of STING.
| Cas No. | 314054-00-7 |
|---|---|
| Purity | ≥99% |
| Formula | C11H7IN2O4 |
| Formula Wt. | 358.09 |
| IUPAC Name | N-(4-iodophenyl)-5-nitrofuran-2-carboxamide |
| Synonym | STING Inhibitor C-176, C176, C 176 |
| Appearance | Yellow solid |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| Info Sheet |
|---|
Yang M, Ma Y, Zhi Y, et al. Inhibitors of IFN gene stimulators (STING) improve intestinal ischemia-reperfusion-induced acute lung injury by activating AMPK signaling. Eur J Med Res. 2022 May 31;27(1):79. PMID: 35642042
Kong L, Li W, Wang W, et al. mtDNA-STING axis mediates microglial polarization via IRF3/NF-kappaB signaling after ischemic stroke. Front Immunol. 2022 Apr 5;13:860977. PMID: 35450066
Li X, Zhang Z, Yu Y, et al. Activation of the STING-IRF3 pathway involved in psoriasis with diabetes mellitus. J Cell Mol Med. 2022 Apr;26(8):2139-2151. PMID: 35174638
Nitrosourea-amino sugar conjugate, DNA cross-li...
Thienylbutyl ITC analog.
Inhibitor of Abl, c-Kit, and PDGFR.
Peptide found in molluscs, cardiomodulator.
Trichothecene mycotoxin produced by Fusarium.
β-lactam carbapenem; penicillin binding protei...
Acyclic nucleotide (adenosine) analog, adefovir...
Diarylheptanoid found in Zingiberaceae.
Xanthine oxidase inhibitor.
Lactone found in fungi such as Eupenicillium; g...
MAO-A/B inhibitor.
Synthetic derivative of vasicine, mucolytic.
Sesquiterpene alcohol found in various essentia...
Endogenous peptide, involved in water/Na+ homeo...
CDK inhibitor, L-type Ca2+ channel blocker.
ROS1, MET, Ron, Axl, TIE-2, VEGFR2 inhibitor.
Synthetic glutathione peroxidase mimetic; yeast...
Synthetic fluorinated thiamphenicol analog; pro...
c-MET, Tie-2, VEGFR inhibitor.
Imidazole; 14-α demethylase inhibitor.