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Canthaxanthin

Canthaxanthin

Product ID C0168
Cas No. 514-78-3
Purity ≥9% (product contains stabilizers)
Product Unit SizeCostQuantityStock
5 g $119.00 In stock
10 g $149.60 In stock
25 g $246.10 In stock
Bulk Quote

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  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Canthaxanthin is a carotenoid terpene pigment initially found in various sources including plants and fish. Canthaxanthin exhibits immunostimulatory, antioxidative, and chemopreventive activities; it does not display any vitamin A activity. In vivo, canthaxanthin increases cell-mediated and humoral immune responses. Metabolites of canthaxanthin enhance gap junction communication and expression of connexin 43. In vitro, canthaxanthin inhibits t-BOOH-induced production of malondialdehyde and lipid peroxidation; it also scavenges radicals. In other cellular models, this compound inhibits MCA-induced neoplastic transformation, suppressing carcinogenesis.

Product Info

Cas No.

514-78-3

Purity

≥9% (product contains stabilizers)

Formula

C40H52O2

Formula Wt.

564.84

Chemical Name

β,β-Carotene-4,4'-dione

IUPAC Name

2,4,4-trimethyl-3-[(1E,3E,5E,7E,9E,11E,13E,15E,17E)-3,7,12, 16-tetramethyl-18-(2,6,6-trimethyl-3-oxocyclohexen-1-yl)octadeca-1,3,5, 7,9,11,13,15,17-nonaenyl]cyclohex-2-en-1-one

Melting Point

217°C(dec.)

Solubility

Soluble in chloroform or oil. Slightly soluble in methanol.

Appearance

Violet to reddish-brown colored crystalline solid

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

C0168 MSDS PDF

Info Sheet

C0168 Info Sheet PDF

References

Chew BP, Park JS. Carotenoid action on the immune response. J Nutr. 2004 Jan;134(1):257S-261S. PMID: 14704330.

Stahl W, Sies H. The role of carotenoids and retinoids in gap junctional communication. Int J Vitam Nutr Res. 1998;68(6):354-9. PMID: 9857261.

Palozza P, Luberto C, Ricci P, et al. Effect of beta-carotene and canthaxanthin on tert-butyl hydroperoxide-induced lipid peroxidation in murine normal and tumor thymocytes. Arch Biochem Biophys. 1996 Jan 15;325(2):145-51. PMID: 8561491.

Pung A, Rundhaug JE, Yoshizawa CN, et al. Beta-carotene and canthaxanthin inhibit chemically- and physically-induced neoplastic transformation in 10T1/2 cells. Carcinogenesis. 1988 Sep;9(9):1533-9. PMID: 3136943.

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