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Cefoperazone Acid

Cefoperazone Acid

Product ID C1629
Cas No. 62893-19-0
Purity ≥98%
Product Unit SizeCostQuantityStock
250 mg $60.10 In stock
1 g $132.60 In stock
5 g $408.30 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Cefoperazone is a third generation β-lactam cephalosporin antibiotic. Cefoperazone exhibits antibacterial efficacy against gram positive and gram negative bacteria, inhibiting penicillin binding proteins to prevent peptidoglycan synthesis and bacterial cell wall formation. Cefoperazone also inhibits mammalian mRNA splicing and is often given in combination with the β-lactamase sulbactam.

Product Info

Cas No.

62893-19-0

Purity

≥98%

Formula

C25H27N9O8S2

Formula Wt.

645.47

Chemical Name

(6R,7R)-7-[[(2R)-[[(4-Ethyl-2,3-dioxo-1-piperazinyl)- carbonyl]amino](4-hydroxyphenyl)acetyl]amino]-3- [[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-5- thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

IUPAC Name

(6R,7R)-7-[[2-[(4-ethyl-2, 3-dioxopiperazine-1-carbonyl)amino]-2-(4-hydroxyphenyl)acetyl]amino]-3-[ (1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0] oct-2-ene-2-carboxylic acid

Melting Point

169-171°C

Appearance

White or Almost White Crystalline Powder

Shipping and Storage

Store Temp

4°C

Ship Temp

Ambient

Downloads

MSDS

C1629 MSDS PDF

Info Sheet

C1629 Info Sheet PDF

References

Aukema KG, Chohan KK, Plourde GL, et al. Small molecule inhibitors of yeast pre-mRNA splicing. ACS Chem Biol. 2009 Sep 18;4(9):759-68. PMID: 19634919.

Mohanty S, Singhal R, Sood S, et al. Comparative in vitro activity of beta-lactam/beta-lactamase inhibitor combinations against gram negative bacteria. Indian J Med Res. 2005 Nov;122(5):425-8. PMID: 16456257.

Yotsuji A, Mitsuyama J, Hori R, et al. Mechanism of action of cephalosporins and resistance caused by decreased affinity for penicillin-binding proteins in Bacteroides fragilis. Antimicrob Agents Chemother. 1988 Dec;32(12):1848-53. PMID: 3266730.

Custom Order

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