LKT Labs

Biochemicals for Life Science Research

Cytarabine

Cytarabine

Product ID C9778
Cas No. 147-94-4
Purity ≥98%
Product Unit SizeCostQuantityStock
100 mg $52.00 In stock
500 mg $139.00 In stock
1 g $225.00 In stock
Bulk Quote

Quicklinks

Description

Cytarabine is a cytosine nucleoside analog that exhibits anticancer chemotherapeutic and antiviral activities. This antimetabolite is clinically used to treat chronic lymphocytic leukemia (CLL), acute lymphocytic leukemia (ALL), and non-Hodgkin lymphoma. Cytarabine inhibits RNA polymerase and DNA polymerase, preventing DNA synthesis. Although it is too toxic for antiviral use, cytarabine inhibits the growth or replication of herpesviruses such as varicella-zoster and cytomegalovirus (CMV).

Product Info

Cas No.

147-94-4
Purity

≥98%
Formula

C9H13N3O5
Formula Wt.

243.22
Chemical Name

4-Amino-1-β-D-arabinofuranosyl-2(1H)-pyrimidinone
IUPAC Name

4-amino-1-[(2R,3S,4S,5R)-3, 4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
Synonym

Alexan, Arabitin, Ara-C, Cytosar, Erpalfa, Iretin, Udicil
Melting Point

212-213°C
Solubility

Soluble in water to 100 mM, DMSO to 50 mM, ethanol.

Appearance

White Crystal Powder

Shipping and Storage

Store Temp

Ambient
Ship Temp

Ambient

Downloads

MSDS

C9778 MSDS PDF
Info Sheet

C9778 Info Sheet PDF

References

Abdel-Aziz W, Jiang HY, Hickey RJ, et al. Ara-C affects formation of cancer cell DNA synthesome replication intermediates. Cancer Chemother Pharmacol. 2000;45(4):312-9. PMID: 10755320.

Hiddemann W. Cytosine arabinoside in the treatment of acute myeloid leukemia: the role and place of high-dose regimens. Ann Hematol. 1991 Apr;62(4):119-28. PMID: 2031974.

Lauter CB, Bailey EJ, Lerner AM. Assessment of cytosine arabinoside as an antiviral agent in humans. Antimicrob Agents Chemother. 1974 Nov;6(5):598-602. PMID: 15825312.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • F3207

    Fibronectin CS-1 Peptide

    Peptide; α4β1 integrin activator.

    ≥95%
  • I7659

    1-Isothiocyanato-8-(methylsulfonyl)-octane

    ITC, erysolin analog.

    ≥98%
  • R0109

    Racecadotril

    Enkephalinase inhibitor.

    ≥98%
  • C1620

    Ceftiofur Hydrochloride

    β-lactam; penicillin binding protein inhibitor...

    ≥90%
  • N7604

    Naltriben

    δ2OR antagonist.

    ≥95%
  • R3011

    Recombinant TpN 15 protein

    Recombinant protein containing Treponema pallid...

    ≥95%
  • X0254

    Xanthohumol

    Prenylated flavonoid found in Humulus lupulus.<...

    ≥98%
  • T0004

    T2 toxin Triol

    Trichothecene mycotoxin produced by Fusarium; p...

    ≥97%, TLC
  • L8261

    Lupeol

    Triterpene; potential tyrosinase inhibitor.

    ≥98%
  • H9714

    L-5-Hydroxytryptophan

    Endogenous amino acid, precursor of 5-HT and me...

    ≥98%
  • P0253

    Panaxadiol

    Triterpene sapongenin found in species of Panax...

    ≥98%
  • T0102

    7-epi-Taxol

    Taxane found in Taxus; potential microtubule de...

    ≥95%
  • P2919

    L-Phenylalaninol

    Non-essential amino acid alcohol.

    ≥98%
  • F5869

    N-formyl-Met-Ala-Ser

    Peptide, involved in neutrophil activation; FPR...

    ≥95%
  • T3468

    Tirapazamine

    Topoisomerase II inhibitor, RPA modulator.

    ≥98%
  • I1418

    Idebenone

    Synthetic quinone CoQ analog, promotes mitochon...

    ≥98%
  • L1983

    Leucomyosuppressin

    Peptide found in insects.

    ≥95%
  • B1876

    Betamethasone

    Steroid; glucocorticoid agonist.

    ≥98%
  • V5870

    Vortioxetine

    5-HT1A agonist, 5-HT1B partial agonist, 5-HT3A/...

    ≥99%
  • P0245

    Palmatine Chloride Hydrate

    Isoquinoline alkaloid found in Corydalis, Phell...

    ≥96%