• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Ebselen

Ebselen

Product ID E0073
Cas No. 60940-34-3
Purity ≥99%
Product Unit SizeCostQuantityStock
5 mg $98.60 In stock
25 mg $225.30 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Ebselen is a synthetic glutathione peroxidase mimetic that reacts with cysteine residues; it exhibits antimicrobial, antibacterial, anti-diabetic, and antioxidative activities. Ebselen increases ROS and mitochondrial membrane potential, inhibiting GDH function in vitro. Additionally, ebselen inhibits yeast sporulation and binds the Mycobacterium Ag85 complex, preventing outer membrane synthesis. In diabetic rats, this compound prevents hyperglycemia, decreases glucose levels, Hb1Ac, and oxidative stress, and increases β-cell mass.

Product Info

Cas No.

60940-34-3

Purity

≥99%

Formula

C13H9NOSe

Formula Wt.

274.18

IUPAC Name

2-phenyl-1,2-benzoselenazol-3-one

Synonym

2-Phenyl-1,2-benzisoselenazolin-3-one

Melting Point

180-181°C

Solubility

Soluble in DMSO.

Appearance

White Solid

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

E0073 MSDS PDF

Info Sheet

E0073 Info Sheet PDF

References

Azad GK, Singh V, Mandal P, et al. Ebselen induces reactive oxygen species (ROS)-mediated cytotoxicity in Saccharomyces cerevisiae with inhibition of glutamate dehydrogenase being a target. FEBS Open Bio. 2014 Jan 6;4:77-89. PMID: 24490132.

Favrot L, Grzegorzewicz AE, Lajiness DH, et al. Mechanism of inhibition of Mycobacterium tuberculosis antigen 85 by ebselen. Nat Commun. 2013;4:2748. PMID: 24193546.

Mahadevan J, Parazzoli S, Oseid E, et al. Ebselen treatment prevents islet apoptosis, maintains intranuclear Pdx-1 and MafA levels, and preserves β-cell mass and function in ZDF rats. Diabetes. 2013 Oct;62(10):3582-8. PMID: 23801580.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • H1894

    Hexestrol

    Synthetic catechol; ER agonist, microtubule pol...

    ≥98%
  • R5774

    Roscovitine

    CDK inhibitor, L-type Ca2+ channel blocker.

    ≥98%
  • M2408

    MGCD-265 Analog

    MET inhibitor.

    ≥98%
  • W5727

    Wogonoside

    Flavonoid glycoside found in Scutellaria.

    ≥98%
  • J766160

    JTE907

    Selective Cannabinoid receptor 2(CB2) inverse a...

    ≥98%
  • A1370

    Adrenomedullin (22-52), human

    Endogenous peptide hormone, involved in cell gr...

    ≥95%
  • M568270

    Mogroside V

    Triterpenoid

    ≥98%
  • T7044

    Triamcinolone Acetonide Acetate

    Steroid; glucocorticoid agonist.

    ≥97%
  • T8000

    Tubacin

    HDAC6 inhibitor.

    ≥96%
  • R2816

    Recombinant HIV-2 gp36

    Recombinant HIV-1 glycoprotein antigen fragment...

    ≥95%
  • G1869

    Geranylgeraniol

    Diterpene alcohol, geranylgeranyl pyrophosphate...

    ≥85%
  • A706840

    ARV-825

    Degrades of BET proteins.

    ≥99%
  • X1753

    Xenopsin

    Peptide hormone, neurotensin analog found in am...

    ≥95%
  • C5645

    Colchicine

    Found in Colchicum; microtubule polymerization ...

    ≥97%
  • E7731

    17-α-Ethynylestradiol

    Synthetic steroid hormone; ER agonist.

    ≥99%
  • G5875

    Gossypol Acetic Acid

    Bcl-2, Bcl-xl, sialyl transferase inhibitor.

    ≥98%
  • M1777

    R-(−)-α-Methylbenzyl Isothiocyanate

    ITC, used as chiral agent.

    ≥98%
  • A9712

    AZD-6482

    p110β PI3K inhibitor.

    ≥98%
  • O938567

    4-epi-6-Oxodocetaxel

    Docetaxel impurity

    ≥95%
  • A980005

    AZ-5104

    Inhibitor of EGFR.

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only