• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Endomorphin-2

Endomorphin-2

Product ID E5211
Cas No. 141801-26-5
Purity ≥95%
Product Unit SizeCostQuantityStock
5 mg $105.00 In stock
10 mg $210.00 In stock
25 mg $420.00 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Endomorphin-2 is an endogenous agonist at μ-opioid receptors (μORs) in the spinal cord; it exhibits antinociceptive/analgesic, immunosuppressive, and pro-angiogenic activities. Endomorphin-2 increases pain thresholds in animal models of thermal pain and inhibits the formation of antibodies in other cellular models. In HUVECs, this peptide stimulates proliferation, migration, adhesion, and tube formation.

Product Info

Cas No.

141801-26-5

Purity

≥95%

Formula

C32H37N5O5

Formula Wt.

571.68

IUPAC Name

(2S)-1-[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]-N-[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]pyrrolidine-2-carboxamide

Solubility

Soluble in water (0.4 mg/mL).

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

E5211 MSDS PDF

Info Sheet

E5211 Info Sheet PDF

References

Liu NJ, Gintzler AR. Spinal endomorphin 2 antinociception and the mechanisms that produce it are both sex- and stage of estrus cycle-dependent in rats. J Pain. 2013 Nov;14(11):1522-30. PMID: 24084000.

Dai X, Song HJ, Cui SG, et al. The stimulative effects of endogenous opioids on endothelial cell proliferation, migration and angiogenesis in vitro. Eur J Pharmacol. 2010 Feb 25;628(1-3):42-50. PMID: 19932695.

Anton B, Leff P, Calva JC, et al. Endomorphin 1 and endomorphin 2 suppress in vitro antibody formation at ultra-low concentrations: anti-peptide antibodies but not opioid antagonists block the activity. Brain Behav Immun. 2008 Aug;22(6):824-32. PMID: 18374539.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • V3278

    Vitamin E Acetate

    Vitamin E analog, antioxidant.

    ≥98%
  • H9612

    Hydrocortisone 21-Acetate

    Steroid hormone involved in stress signaling; g...

    ≥98%
  • P2995

    Physcion

    Anthraquinone found in various plant sources.

    ≥96%
  • P8270

    Purvalanol A

    Purine derivative; CDK inhibitor.

    ≥98%
  • T3097

    Thymosin α-1 Acetate

    Endogenous peptide, involved in hormone regulat...

    ≥95%
  • T8153

    Tunicamycin

    Nucleoside antibiotic mixture; GlcNAc phosphotr...

    ≥98%
  • I4961

    Imperatorin

    Furocoumarin; voltage-gated Na+ channel blocker...

    ≥98%
  • N3584

    Nivalenol

    Trichothecene mycotoxin produced by Fusarium; p...

    ≥98%
  • P0344

    Palbociclib Isethionate

    CDK4/6 inhibitor.

    ≥98%
  • I0481

    Ibuprofen

    NSAID; COX-1/2 inhibitor.

    ≥98%
  • C5592

    CNX-774

    BTK inhibitor.

    ≥98%
  • T5847

    Tolvaptan

    V2 antagonist.

    ≥99%
  • L8277

    [Gln8]-Luteinizing Hormone Releasing Hormone, chicken

    Endogenous peptide hormone, involved in secreti...

    ≥95%
  • L0400

    LB-100

    PP2A inhibitor.

    ≥98%
  • P3198

    Phytanic Acid

    Fatty acid metabolite of chlorophyll; RXR and P...

    ≥97%
  • S1612

    Sedanolide

    Phthalide found in celery seeds; COX-1, COX-2, ...

    ≥98%
  • G2873

    Growth Hormone Releasing Factor, sheep

    Endogenous peptide hormone, involved in growth ...

    ≥95%
  • E4416

    Eledoisin

    Peptide, substance P analog; NK agonist.

    ≥95%
  • T6934

    Trimebutine Maleate

    L-type Ca2+ channel blocker, BK K+ channel modu...

    ≥96%
  • A4806

    Ambroxol Hydrochloride

    Expectorant.

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only