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Enfuvirtide (T-20)

Enfuvirtide (T-20)

Product ID E5220
Cas No. 159519-65-0
Purity ≥95%
Product Unit SizeCostQuantityStock
1 mg $157.50 In stock
2 mg $262.50 In stock
5 mg $472.50 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Enfuvirtide is a synthetic peptide derived from HIV-1 that exhibits antiviral activity. Enfuvirtide inhibits viral fusion, mimicking the amino acid sequence of gp41, preventing fusion of the virus to the host cell membrane. Enfuvirtide may also induce apoptosis in bystander cells.

Product Info

Cas No.

159519-65-0

Purity

≥95%

Formula

C204H301N51O64

Formula Wt.

4462.0

Synonym

T20, Fuzeon, Pentafuside, DP178.

Solubility

Best dissolved in alkaline conditions such as sterile pyrogen free 0.1% NaOH, 1% Na2CO3 or disodium phenyl phosphate at a concentration of 0.1-1 mg/mL. Insoluble in water.

Appearance

White to off white powder

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

E5220 MSDS PDF

Info Sheet

E5220 Info Sheet PDF

References

Tan JJ, Ma XT, Liu C, et al. The current status and challenges in the development of fusion inhibitors as therapeutics for HIV-1 infection. Curr Pharm Des. 2013;19(10):1810-7. PMID: 23092283.

Cai L, Gochin M, Liu K. Biochemistry and biophysics of HIV-1 gp41 - membrane interactions and implications for HIV-1 envelope protein mediated viral-cell fusion and fusion inhibitor design. Curr Top Med Chem. 2011 Dec;11(24):2959-84. PMID: 22044229.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
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