• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Esculin

Esculin

Product ID E7310
Cas No. 531-75-9
Purity ≥98%
Product Unit SizeCostQuantityStock
1 g $57.20 In stock
5 g $105.70 In stock
10 g $168.00 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Esculin is a coumarin glucoside found in Aesculus, Daphne, and Bursaria. Esculin exhibits anti-diabetic and antioxidative activities. Esculin is hydrolyzed by species of Streptococcus, Enterococcus, Listeria, and Aerococcus and is used in research models to identify these bacteria. In diabetic rats, esculin decreases blood glucose and glucose-6-phosphatase levels and increases glucose uptake, potentially through the activation of insulin receptors, Akt, and GSK3β. Additionally, esculin decreases lipid peroxidation and increases levels of glutathione, glutathione peroxidase, glutathione-S-transferase, superoxide dismutase, and catalase in the kidneys of animals treated with pro-oxidant aflatoxin B1.

Product Info

Cas No.

531-75-9

Purity

≥98%

Formula

C15H16O9 • H2O

Formula Wt.

358.30

Chemical Name

6-(β-D-Glucopyranosyloxy)-7-hydroxy-2H-1- benzopyran-2-one

IUPAC Name

7-hydroxy-6-[(2S,3R,4S,5S,6R)-3,4, 5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-2-one

Synonym

Esculin hydrate, Esculoside, Bicolorin, Enallachrome, Polychrome, Escosyl

Melting Point

203-205°C

Solubility

Slightly soluble in water. Soluble in methanol, DMSO (60 mg/mL).

Appearance

White to off white powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

E7310 MSDS PDF

Info Sheet

E7310 Info Sheet PDF

References

Kang KS, Lee W, Jung Y, et al. Protective effect of esculin on streptozotocin-induced diabetic renal damage in mice. J Agric Food Chem. 2014 Mar 5;62(9):2069-76. PMID: 24484395.

Naaz F, Abdin MZ, Javed S. Protective effect of esculin against prooxidant aflatoxin B1-induced nephrotoxicity in mice. Mycotoxin Res. 2014 Feb;30(1):25-32. PMID: 24326591.

Raemy A, Meylan M, Casati S, et al. Phenotypic and genotypic identification of streptococci and related bacteria isolated from bovine intramammary infections. Acta Vet Scand. 2013 Jul 18;55:53. PMID: 23866930.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • A5032

    D,L-Aminoglutethimide

    Aromatase inhibitor.

    ≥98%
  • S1810

    Secnidazole

    Nitroimidazole, binds DNA; nucleic acid synthes...

    ≥98%
  • N0212

    Nedaplatin

    Pt-based DNA cross-linker.

    ≥98%
  • P2816

    S-(N-3-Phenylpropylthiocarbamoyl)-L-cysteine

    Cysteine-ITC conjugate.

    ≥98%
  • M576486

    Mometasone Furoate

    Synthetic glucocorticoid

    ≥98%
  • B030966

    BAY 11-7082

    inhibits inflammatory signaling

    ≥98%
  • S0168

    Saracatinib

    Src and Abl inhibitor.

    ≥98%
  • E6896

    Erysolin

    ITC found in cruciferous vegetables, analog of ...

    ≥97%
  • R3577

    Ritonavir

    HIV protease inhibitor.

    ≥98%
  • A4845

    Amylin (8-37), rat

    Endogenous peptide hormone inolved in gastric e...

    ≥95%
  • V574451

    Volitinib

    c-Met inhibitor.

    ≥98%
  • E6846

    Erlotinib Hydrochloride

    EGFR inhibitor.

    ≥98%
  • C4557

    Clofibrate

    Fibrate; PPARα agonist.

    ≥99%
  • A0819

    Acetylsalicylic Acid

    NSAID; COX-1/2 inhibitor.

    ≥98%
  • Z324098

    Ziconotide

    Non-opioid analgesic.

    ≥95%
  • D6108

    1,4-DPCA

    Prolyl hydroxylase inhibitor.

    ≥98%
  • N0263

    Naphazoline Nitrate

    α1-adrenergic agonist.

    ≥97%
  • N3276

    Nitroso(acetoxymethyl)methylamine

    NNK precursor found in tobacco smoke; carcinoge...

    ≥97%
  • P6802

    Pranoprofen

    NSAID; COX-1/2 inhibitor.

    ≥98%
  • G3461

    Ginsenoside F2

    Triterpene saponin found in species of Panax.

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only