LKT Labs

Biochemicals for Life Science Research

Glycitin

Glycitin

Product ID G4799
Cas No. 40246-10-4
Purity ≥98%
Product Unit SizeCostQuantityStock
5 mg $133.00 In stock
25 mg $592.00 In stock
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Description

Glycitin is a glycosylated isoflavone found in soy that activates bitter taste receptors (TAS2Rs). Glycitin exhibits anticancer chemotherapeutic and anti-osteoporotic properties. Glycitin inhibits the expression of matrix metalloproteinases 3 and 9 and suppresses invasive activity of glioma cells in vitro. Glycitin also exhibits effects on bone formation. This compound increases proliferation of mouse bone marrow stromal cells and osteoblasts and inhibits adipogenesis of bone marrow stromal cells as well as adipocytic transdifferentiation of osteoblasts. Like glycitein, this compound may act as a phytoestrogen.

Product Info

Cas No.

40246-10-4
Purity

≥98%
Formula

C22H22O10
Formula Wt.

446.40
Chemical Name

3-(4-hydroxyphenyl)-6-methoxy-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one
IUPAC Name

3-(4-hydroxyphenyl)-6-methoxy-7-[(2S,3R,4S,5S,6R)-3,4, 5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one
Synonym

Glycitein 7-O-glucoside
Solubility

Soluble in DMSO poorly; insoluble in other solvents
Appearance

White to off white powder

Shipping and Storage

Store Temp

Ambient
Ship Temp

Ambient

Downloads

MSDS

G4799 MSDS PDF
Info Sheet

G4799 Info Sheet PDF

References

Roland WS, Vincken JP, Gouka RJ, et al. Soy isoflavones and other isoflavonoids activate the human bitter taste receptors hTAS2R14 and hTAS2R39. J Agric Food Chem. 2011 Nov 9;59(21):11764-71. PMID: 21942422.

Lee EJ, Kim SY, Hyun JW, et al. Glycitein inhibits glioma cell invasion through down-regulation of MMP-3 and MMP-9 gene expression. Chem Biol Interact. 2010 Apr 15;185(1):18-24. PMID: 20188714.

Li XH, Zhang JC, Sui SF, et al. Effect of daidzin, genistin, and glycitin on osteogenic and adipogenic differentiation of bone marrow stromal cells and adipocytic transdifferentiation of osteoblasts. Acta Pharmacol Sin. 2005 Sep;26(9):1081-6. PMID: 16115375.

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