Name: GSK-2636771
SKU: G7346
Availability: InStock

Description

GSK-2636771 is an inhibitor of the p110β isoform of PI3K. GSK-2636771 displays anticancer chemotherapeutic activity in PTEN-deficient cancers such as glioblastomas, prostate cancers, and endometrial cancers. This compound is currently in clinical trials.

Product Info

Cas No.	1372540-25-4
Purity	≥98%
Formula	C₂₂H₂₂F₃N₃O₃
Formula Wt.	433.42
IUPAC Name	2-methyl-1-[[2-methyl-3-(trifluoromethyl)phenyl]methyl]-6-morpholin-4- ylbenzimidazole-4-carboxylic acid
Solubility	Soluble in DMSO(28mg/ml), and water with 1 eq. of base, insoluble in ethanol
Appearance	White Powder

Shipping and Storage

Store Temp	-20°C
Ship Temp	Ambient

Downloads

MSDS	G7346 MSDS PDF
Info Sheet	G7346 Info Sheet PDF
Brochures	PI3K-Akt-mTORC Pathway Booklet

References

Weigelt B, Warne PH, Lambros MB, et al. PI3K Pathway Dependencies in Endometrioid Endometrial Cancer Cell Lines. Clin Cancer Res. 2013 Jul 1;19(13):3533-44. PMID: 23674493.

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GSK-2636771

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