Description
GSK3685032 is an inhibitor of DNA methyltransferase 1.
GSK3685032
Product ID G733404
Cas No. 2170137-61-6
Purity ≥98%
| Product Unit Size | Cost | Quantity | Stock |
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Product Info
| Cas No. | 2170137-61-6 |
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| Purity | ≥98% |
| Formula | C22H24N6OS |
| Formula Wt. | 420.54 |
| IUPAC Name | 2-[6-(4-aminopiperidin-1-yl)-3,5-dicyano-4-ethylpyridin-2-yl]sulfanyl-2-phenylacetamide |
| Synonym | GSK-3685032 |
Shipping and Storage
| Store Temp | -20°C |
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| Ship Temp | Ambient |
Downloads
| Info Sheet |
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References
Wiseman A, Tiedemann R, Fan H, et al. Chromosome-specific retention of cancer-associated DNA hypermethylation following pharmacological inhibition of DNMT1. Commun Biol. 2022 Jun 2;5(1):528. PMID: 35654826
Pappalardi M, Keenan K, Cockerill M, et al. Discovery of a first-in-class reversible DNMT1-selective inhibitor with improved tolerability and efficacy in acute myeloid leukemia. Nat Cancer. 2021 Oct;2(10):1002-1017. PMID: 34790902