LKT Labs

Biochemicals for Life Science Research

GSK3685032

GSK3685032

Product ID G733404
Cas No. 2170137-61-6
Purity ≥98%
Product Unit SizeCostQuantityStock
1 mg $61.00 In stock
5 mg $243.00 In stock
10 mg $425.00 In stock
25 mg $662.00 In stock
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Description

GSK3685032 is an inhibitor of DNA methyltransferase 1.

Product Info

Cas No.

2170137-61-6
Purity

≥98%
Formula

C22H24N6OS
Formula Wt.

420.54
IUPAC Name

2-[6-(4-aminopiperidin-1-yl)-3,5-dicyano-4-ethylpyridin-2-yl]sulfanyl-2-phenylacetamide
Synonym

GSK-3685032

Shipping and Storage

Store Temp

-20°C
Ship Temp

Ambient

Downloads

Info Sheet

G733404 Info Sheet PDF

References

Wiseman A, Tiedemann R, Fan H, et al. Chromosome-specific retention of cancer-associated DNA hypermethylation following pharmacological inhibition of DNMT1. Commun Biol. 2022 Jun 2;5(1):528. PMID: 35654826

Pappalardi M, Keenan K, Cockerill M, et al. Discovery of a first-in-class reversible DNMT1-selective inhibitor with improved tolerability and efficacy in acute myeloid leukemia. Nat Cancer. 2021 Oct;2(10):1002-1017. PMID: 34790902

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