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Guanylin, human

Guanylin, human

Product ID G8103
Cas No. 183200-12-6
Purity ≥95%
Product Unit SizeCostQuantityStock
0.5 mg $194.30 In stock
1 mg $367.50 In stock
2.5 mg $735.00 Please Inquire
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Guanylin is a gastrointestinal peptide hormone that activates guanyl cyclase C primarily in intestinal epithelial cells, but also in neurons. Guanylin increases intracellular levels of cGMP and induces natriuresis and diuresis in the kidney. Guanylin inhibits cell proliferation of colonic cells, inducing cell cycle arrest.

Product Info

Cas No.

183200-12-6

Purity

≥95%

Formula

C58H87N15O21S4

Formula Wt.

1458.68

Solubility

Soluble in water (1 mg/mL).

Appearance

White to off white powder

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

G8103 MSDS PDF

Info Sheet

G8103 Info Sheet PDF

References

Basu N, Saha S, Khan I, et al. Intestinal cell proliferation and senescence are regulated by receptor guanylyl cyclase C and p21. J Biol Chem. 2014 Jan 3;289(1):581-93. PMID: 24217248.

Fonteles MC, do Nascimento NR. Guanylin peptide family: history, interactions with ANP, and new pharmacological perspectives. Can J Physiol Pharmacol. 2011 Aug;89(8):575-85. PMID: 21815750.

Forte LR, Freeman RH, Krause WJ, et al. Guanylin peptides: cyclic GMP signaling mechanisms. Braz J Med Biol Res. 1999 Nov;32(11):1329-36. PMID: 10559833.

Custom Order

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  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
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