Description
Gusacitinib is a dual inhibitor of SYK/JAK kinases.
Product Unit Size | Cost | Quantity | Stock |
---|
Gusacitinib is a dual inhibitor of SYK/JAK kinases.
Cas No. | 1425381-60-7 |
---|---|
Purity | ≥98% |
Formula | C24H28N8O2 |
Formula Wt. | 460.54 |
IUPAC Name | 2-[1-[4-[4-(4-hydroxypiperidin-1-yl)anilino]-5-oxo-6H-pyrimido[4,5-d]pyridazin-2-yl]piperidin-4-yl]acetonitrile |
Synonym | ASN-002, ASN002 |
Appearance | Yellow powder |
Store Temp | -20°C |
---|---|
Ship Temp | Ambient |
Info Sheet |
---|
Montilla A, Gomez-Garcia F, Gomez-Arias P, et al. Scoping review on the use of drugs targeting JAK/STAT pathway in atopic dermatitis, vitiligo, and alopecia areata. Dermatol The (Heidelb). 2019 Dec;9(4):655-683. PMID: 31606872
Peptide, derivative of AT II, involved in vasoc...
Steroid; glucocorticoid agonist.
(S) isomer of omeprazole; H+/K+ ATPase and MAO-...
Xanthine alkaloid found in coffee, tea, and oth...
AurKB/C inhibitor.
Polyketide; CRM1 inhibitor.
β-lactam; penicillin binding protein inhibitor...
Mineralocorticoid antagonist.
Tryptamine; 5-HT1B/1D agonist, TRPV1 antagonist...
Glucocorticoid
T-type Ca2+ and voltage-gated Na+ channel block...
Akt inhibitor.
Opioid peptide; δOR agonist.
Loop diuretic; NKCC symporter and HSP90 inhibit...
Phenothiazine derivative; D1/2 and 5-HT1A/2A an...
CDK4/6 inhibitor.
EGFR inhibitor.
TRPV4 agonist
Cannabinoid receptor 2 selective agonist.
c-MET, Tie-2, VEGFR inhibitor.