Description
H7 is an inhibitor of PKC and PKG that is used to study the effects of protein kinase signaling in research models.
H7 is an inhibitor of PKC and PKG that is used to study the effects of protein kinase signaling in research models.
| Cas No. | 108930-17-2 |
|---|---|
| Purity | ≥98% |
| Formula | C14H17N3O2S • 2HCl |
| Formula Wt. | 364.30 |
| IUPAC Name | 5-(2-methylpiperazin-1-yl)sulfonylisoquinoline;dihydrochloride |
| Synonym | (-)-1-(5-Isoquinolinesulfonyl)-2-methylpiperazine di-HCl salt |
| Melting Point | 215-225°C |
| Solubility | Soluble in water. |
| Store Temp | 4°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Chen JJ, Zhang J, Cai Y, et al. C-type natriuretic peptide inhibiting vascular calcification might involve decreasing bone morphogenic protein 2 and osteopontin levels. Mol Cell Biochem. 2014 Jul;392(1-2):65-76. PMID: 24710639.
Zhang Y, Bao S, Kuang Z, et al. Urotensin II promotes monocyte chemoattractant protein-1 expression in aortic adventitial fibroblasts of rat. Chin Med J (Engl). 2014 May;127(10):1907-12. PMID: 24824254.
α1-Adrenergic antagonist.
Synthesis intermediate
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Peptide, substance P analog; NK agonist.
beta-Amyloid anti-oligomer and aggregation inhi...
AChE and BChE inhibitor.
O-methylated coumarin; Ca2+ channel blocker.
mTOR inhibitor.
Indoleamine 2,3-dioxygenase inhibitor.
Alkylphospholipid analog; Akt inhibitor.
SYK/JAK inhibitor
Benzimidazole; microtubule polymerization inhib...
Inhibits NS5A
Inhibitor of VEGFR1/2/3.
Synthetic steroid hormone; AR agonist, ER and P...
BCL-XL specific degrader
Aromatase inhibitor.
Potential p53 activator or SIRT2 inhibitor.
GABA-A agonist.