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Iberverin

Iberverin

Product ID I0418
Cas No. 505-79-3
Purity ≥98%
Product Unit SizeCostQuantityStock
25 mg $180.20 In stock
50 mg $311.40 In stock
100 mg $539.70 In stock
500 mg $1,823.10 Please Inquire
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
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  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Iberverin is a sulforaphane homolog found in cruciferous vegetables. This isothiocyanate (ITC) exhibits antioxidative activity. Iberverin induces phase II enzymes, increasing glutathione-S-transferase and quinone reductase expression in vivo. Additionally, iberverin increases expression of Nrf2, γ-glutamylcysteine synthetase, and heme oxygenase 1 (HO-1). Iberverin displays chemopreventive potential, decreasing expression of androgen receptors (ARs) in prostate cancer cells.

Product Info

Cas No.

505-79-3

Purity

≥98%

Formula

C5H9NS2

Formula Wt.

147.26

Chemical Name

1-Isothiocyanato-3-(methylsulfenyl)-propane

IUPAC Name

1-isothiocyanato-3-methylsulfanylpropane

Synonym

1-Isothiocyanato-3-(methylthio)propane, 3-Methyl- mercaptopropyl isothiocyanate, 3-Methylthiopropyl isothiocyanate

Solubility

Soluble in ethanol, most organic solvents.

Appearance

Yellow Liquid

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

I0418 MSDS PDF

Info Sheet

I0418 Info Sheet PDF

References

Ernst IM, Palani K, Esatbeyoglu T, et al. Synthesis and Nrf2-inducing activity of the isothiocyanates iberverin, iberin and cheirolin. Pharmacol Res. 2013 Apr;70(1):155-62. PMID: 23403058.

Kim SH, Singh SV. D,L-Sulforaphane causes transcriptional repression of androgen receptor in human prostate cancer cells. Mol Cancer Ther. 2009 Jul;8(7):1946-54. PMID: 19584240.

Munday R, Munday CM. Induction of phase II detoxification enzymes in rats by plant-derived isothiocyanates: comparison of allyl isothiocyanate with sulforaphane and related compounds. J Agric Food Chem. 2004 Apr 7;52(7):1867-71. PMID: 15053522.

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