• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Isoflurane

Isoflurane

Product ID I7258
Cas No. 26675-46-7
Purity ≥98%
Product Unit SizeCostQuantityStock
250 mg $58.50 In stock
1 g $84.30 In stock
5 g $110.40 In stock
25 g $162.30 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Isoflurane is an anesthetic most commonly used in veterinary medicine. Isoflurane exhibits cardiomodulatory, neuromodulatory, and pro-inflammatory activities. In diabetic rats, isofluorane decreases cardiac force and intracellular Ca2+ amplitude. Isoflurane also increases IL-6 and NF-κB levels in glioma cells and microglia. In other cellular models, isoflurane inhibits L-type voltage-gated Ca2+ channel currents at resting membrane potential. Additionally, isofluorane binds and modulates signaling by ATP synthase and NADH dehydrogenase. Isoflurane also inhibits delayed rectifier and A-type K+ channels and NMDA receptors, activates Ca2+ ATPase and ATP-sensitive K+ channels, and potentiates GABA-A and glycine (GlyR) receptors.

Product Info

Cas No.

26675-46-7

Purity

≥98%

Formula

C3H2ClF5O

Formula Wt.

184.49

Chemical Name

2-chloro-2-(difluoromethoxy)-1,1,1-trifluoroethane

IUPAC Name

2-chloro-2-(difluoromethoxy)-1,1,1-trifluoroethane

Synonym

1-Chloro-2,2,2-trifluoroethyl difluoromethyl ether; Forane; 2-Chloro-2-(difluoromethoxy)-1,1,1-trifluoroethane

Solubility

Soluble in water (4.47 mg/ml at 37 °C), and organic liquids including fats and oils

Appearance

Clear and Colorless mobile heavy liquid

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

I7258 MSDS PDF

Info Sheet

I7258 Info Sheet PDF

References

Shen X, Bhatt N, Xu J, et al. Effect of isoflurane on myocardial energetic and oxidative stress in cardiac muscle from zucker diabetic Fatty rat. J Pharmacol Exp Ther. 2014 Apr;349(1):21-8. PMID: 24431470.

Fanchaouy M, Cubano L, Maldonado H, et al. PKC independent inhibition of voltage gated calcium channels by volatile anesthetics in freshly isolated vascular myocytes from the aorta. Cell Calcium. 2013 Oct;54(4):257-65. PMID: 23948226.

Zhang L, Zhang J, Yang L, et al. Isoflurane and sevoflurane increase interleukin-6 levels through the nuclear factor-kappa B pathway in neuroglioma cells. Br J Anaesth. 2013 Jun;110 Suppl 1:i82-91. PMID: 23604542.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • A5280

    Angiotensin II (3-8), human

    Endogenous peptide fragment, involved in vasoco...

    ≥95%
  • N1989

    Neurotensin

    Endogenous neuropeptide involved in hormone rel...

    ≥95%
  • M704789

    MRTX1133

    KRAS inhibitor

    ≥98%
  • S8345

    S-(−)-Sulpiride

    GHB agonist, D2/3 antagonist.

    ≥99%
  • H1892

    Hexamethylene Bisacetamide

    HEXIM1 activator.

    ≥99%
  • C2844

    Chloramphenicol

    Protein translation inhibitor, peptidyl transfe...

    ≥98%
  • C1660

    CEP-32496

    V600E B-Raf inhibitor.

    ≥98%
  • P0369

    Parecoxib Sodium

    NSAID; COX-2 inhibitor.

    ≥99%
  • J8800

    JW55

    TNKS1/2 inhibitor.

    ≥98%
  • B5075

    BMS-708163

    γ-Secretase inhibitor.

    ≥98%
  • R3374

    Risedronic Acid

    Bisphosphonate; inhibits transfer of farnesyl p...

    ≥97%
  • S0500

    SB-203580

    p38 MAPK inhibitor.

    ≥98%
  • T5604

    Tobramycin, Free Base

    Aminoglycoside; protein translation inhibitor.<...

    ≥98%
  • I7659

    1-Isothiocyanato-8-(methylsulfonyl)-octane

    ITC, erysolin analog.

    ≥98%
  • C0824

    CCG1423

    Serum response factor inhibitor and MRTF-A bind...

    ≥98%
  • C022682

    2-Carbomethoxy-3-thiophenesulfonyl Chloride

    Building block

    ≥98%
  • T0110

    Taxane Standard Mixture

    Mixture of taxanes.

    ≥98%
  • E6376

    Eptifibatide

    Glycoprotein IIb/IIIa inhibitor.

    ≥98%
  • B8075

    4-tert-Butyl-5-Methoxy-1,2-quinone

    BHA derivative.

    ≥95%
  • T1844

    Telbivudine

    Nucleoside (thymidine) analog; DNA chain termin...

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only