Description
KGDS is a synthetic peptide derived from fibrinogen. KGDS activates the glycoprotein IIb/IIIa receptor, inhibiting fibrinogen-platelet binding and thrombin activity.
KGDS is a synthetic peptide derived from fibrinogen. KGDS activates the glycoprotein IIb/IIIa receptor, inhibiting fibrinogen-platelet binding and thrombin activity.
| Purity | ≥95% |
|---|---|
| Formula | C15H27N5O8 |
| Formula Wt. | 405.41 |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| Info Sheet |
|---|
Knapp A, Degenhardt T, Dodt J. Hirudisins. Hirudin-derived thrombin inhibitors with disintegrin activity. J Biol Chem. 1992 Dec 5;267(34):24230-4. PMID: 1447173.
Parise LV, Helgerson SL, Steiner B, et al. Synthetic peptides derived from fibrinogen and fibronectin change the conformation of purified platelet glycoprotein IIb-IIIa. J Biol Chem. 1987 Sep 15;262(26):12597-602. PMID: 2957377.
V600E B-Raf inhibitor.
Peptide; GABA potentiator, NMDA negative allost...
p110α PI3K inhibitor.
Sesquiterpene lactone derived from Artemesia.
Flavanol originally found in Camilla (green tea...
Azapirone; α1-adrenergic and 5-HT1A partial ag...
AT1 antagonist.
Macrolide lactone found in Bugula; TLR4 activat...
Phytoalexin
Induces activation of Nrf2; inhibits apoptosis ...
Synthesis impurity
Endogenous peptide hormone fragment, involved i...
HDAC1/2/3/11 inhibitor.
Alkylphenol found in Ginkgo; HIV protease inhib...
Endogenous sterol component of animal cell memb...
Synthetic vitamin E, antioxidant.
ALK4/5/7 (activin-like) inhibitor, TGF-β inhib...
Alkaloid found in Sophora.
NS3/4A inhibitor
Prodrug