Description
KGDS is a synthetic peptide derived from fibrinogen. KGDS activates the glycoprotein IIb/IIIa receptor, inhibiting fibrinogen-platelet binding and thrombin activity.
KGDS is a synthetic peptide derived from fibrinogen. KGDS activates the glycoprotein IIb/IIIa receptor, inhibiting fibrinogen-platelet binding and thrombin activity.
| Purity | ≥95% |
|---|---|
| Formula | C15H27N5O8 |
| Formula Wt. | 405.41 |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| Info Sheet |
|---|
Knapp A, Degenhardt T, Dodt J. Hirudisins. Hirudin-derived thrombin inhibitors with disintegrin activity. J Biol Chem. 1992 Dec 5;267(34):24230-4. PMID: 1447173.
Parise LV, Helgerson SL, Steiner B, et al. Synthetic peptides derived from fibrinogen and fibronectin change the conformation of purified platelet glycoprotein IIb-IIIa. J Biol Chem. 1987 Sep 15;262(26):12597-602. PMID: 2957377.
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