Name: Lomustine
SKU: L5648
Availability: InStock

Description

Lomustine is a nitrosourea alkylator that exhibits anticancer chemotherapeutic activity. Lomustine is clinically used to treat various forms of cancer and is one component of the “PCV” regimen.

Product Info

Cas No.	13010-47-4
Purity	≥98%
Formula	C₉H₁₆ClN₃O₂
Formula Wt.	233.70
Chemical Name	N-(2-Chloroethyl)-N'-cyclohexyl-N-nitrosourea
IUPAC Name	1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea
Synonym	Belustine, Cecenu' CeeNU, CiNU
Melting Point	90°C
Solubility	Soluble in ethanol (45 mg/mL), chloroform, acetone, DMSO (45 mg/mL).
Appearance	Yellowish Crystal

Shipping and Storage

Store Temp	4°C
Ship Temp	Ambient

Downloads

MSDS	L5648 MSDS PDF
Info Sheet	L5648 Info Sheet PDF

References

Buccheri G, Ferrigno D, Rosso A. A phase II study of methotrexate, doxorubicin, cyclophosphamide, and lomustine chemotherapy and lonidamine in advanced non-small cell lung cancer. Cancer. 1993 Sep 1;72(5):1564-72. PMID: 8394198.

Kamiya S. Synthesis of antitumor nitrosourea derivatives and chemical studies of their mechanism of action. Eisei Shikenjo Hokoku. 1986;(104):1-19. PMID: 3471287.

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