Description
Lomustine is a nitrosourea alkylator that exhibits anticancer chemotherapeutic activity. Lomustine is clinically used to treat various forms of cancer and is one component of the “PCV” regimen.
Product Unit Size | Cost | Quantity | Stock |
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Lomustine is a nitrosourea alkylator that exhibits anticancer chemotherapeutic activity. Lomustine is clinically used to treat various forms of cancer and is one component of the “PCV” regimen.
Cas No. | 13010-47-4 |
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Purity | ≥98% |
Formula | C9H16ClN3O2 |
Formula Wt. | 233.70 |
Chemical Name | N-(2-Chloroethyl)-N'-cyclohexyl-N-nitrosourea |
IUPAC Name | 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea |
Synonym | Belustine, Cecenu' CeeNU, CiNU |
Melting Point | 90°C |
Solubility | Soluble in ethanol (45 mg/mL), chloroform, acetone, DMSO (45 mg/mL). |
Appearance | Yellowish Crystal |
Store Temp | 4°C |
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Ship Temp | Ambient |
MSDS | |
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Info Sheet |
Buccheri G, Ferrigno D, Rosso A. A phase II study of methotrexate, doxorubicin, cyclophosphamide, and lomustine chemotherapy and lonidamine in advanced non-small cell lung cancer. Cancer. 1993 Sep 1;72(5):1564-72. PMID: 8394198.
Kamiya S. Synthesis of antitumor nitrosourea derivatives and chemical studies of their mechanism of action. Eisei Shikenjo Hokoku. 1986;(104):1-19. PMID: 3471287.
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